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1318 articles
October 202624
Measurement Properties of Hand-Held Dynamometry for Ankle Strength Assessment: A COSMIN-Based Systematic Review and Meta-Analysis.
This COSMIN-based systematic review and meta-analysis assessed handheld dynamometry (HHD) for measuring isometric ankle muscle strength in healthy individuals.
Efficacy and safety of GLP-1 receptor agonists for antipsychotic-related overweight and metabolic dysregulation: a systematic review and meta-analysis.
This systematic review and meta-analysis pooled randomized controlled trials of GLP-1 receptor agonists in adults receiving antipsychotic treatment for overweight or metabolic dysregulation.
Stereotactic body radiation therapy for pancreatic cancer: evaluating its efficacy, safety, and future prospects: systematic review.
This systematic narrative review assessed stereotactic body radiation therapy (SBRT) for locally advanced pancreatic cancer, including patients unsuitable for surgery.
Influence of capsular tension ring implantation on dynamic in vivo capsular apposition and intraocular lens behavior in highly myopic eyes.
This prospective randomized clinical trial assessed whether capsular tension ring (CTR) implantation affects capsular apposition and intraocular lens (IOL) behavior after cataract surgery in highly myopic eyes.
Cine Magnetic Resonance Imaging for Assessing Chest Wall Invasion in Lung Cancer: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated cine MRI for detecting chest wall invasion in lung cancer, using surgical and histopathologic findings as the reference standard.
Informal Caregiver-Observed Fall Risk Indicators and Caregiver Responses to Prevent Falls Among Community-Dwelling Older People: A Systematic Review.
This systematic review synthesized 16 studies of informal caregivers’ observations of fall-risk indicators and their preventive responses among community-dwelling older people.
Efficacy and safety of mitapivat in patients with sickle cell disease (RISE UP): a phase 3, double-blind, global, randomised, placebo-controlled trial.
RISE UP was a phase 3, double-blind, global, randomised, placebo-controlled trial conducted at 69 sites in 15 countries. It evaluated twice-daily mitapivat in patients older than 16 years with sickle cell disease…
Uniportal versus multiportal robotic-assisted thoracic surgery for anatomical pulmonary resection: a systematic review and meta-analysis of perioperative recovery and surgical quality.
This systematic review and meta-analysis compared uniportal/single-port with multiportal robotic-assisted thoracic surgery for anatomical pulmonary resection.
Digital Therapeutic Interventions for Suicide Prevention: A Systematic Review and Meta-Analysis of Their Effectiveness in Reducing Suicidal Ideation and Suicide Attempts.
This systematic review and meta-analysis synthesised randomized clinical trials of digital interventions for suicide prevention. Seventeen studies (N = 5.089) were included.
Effect of Rapid Rollover on Pneumothorax Rate After Percutaneous CT-Guided Lung Biopsy: A Multisite Randomized Controlled Trial Within a Single Health System.
This prospective, multisite randomized controlled trial evaluated rapid rollover after CT-guided lung biopsy using an anterior or lateral approach.
Feasibility of a Co-Designed Personalized Cognitive Reablement Program Delivered via Digital Voice Assistants for Older Adults Living With Early-Stage Dementia or Mild Cognitive Impairment: Pilot Randomized Controlled Trial.
This nonblinded pilot randomized controlled trial assessed the feasibility and potential effectiveness of VOICE-COG, a personalized cognitive reablement program delivered through digital voice assistants, in adults aged…
Skeletal effects of GLP-1 receptor agonist therapy in adults with overweight or obesity: a systematic review.
This systematic review examined randomized evidence on bone mineral density (BMD) and bone-turnover markers in adults with overweight or obesity receiving GLP-1 receptor agonists.
Extracorporeal photopheresis for the treatment of steroid-refractory immune related adverse events from immune checkpoint inhibitor therapy: a multi-center phase Ib/II clinical trial.
This prospective, single-arm, non-randomized phase Ib/II multicentre trial evaluated extracorporeal photopheresis (ECP) for steroid-refractory immune-related adverse events (irAEs) in 30 patients receiving immune…
Evaluation of the Achievement of a Pharmacodynamic Target of Piperacillin-Tazobactam for the Population With Obesity: An Open Randomized Controlled Feasibility Study (TAZO-OBESITY Trial).
The open-label randomized feasibility trial TAZO-OBESITY compared standard with prolonged piperacillin-tazobactam infusions in patients with obesity (BMI ≥30 kg/m²).
The entorhinal cortex atrophy score for diagnostic distinction between phases of the Alzheimer's disease continuum.
This systematic review assessed the Entorhinal Cortex Atrophy (ERICA) visual score for distinguishing subjective cognitive decline (SCD), mild cognitive impairment (MCI), and Alzheimer’s disease (AD) dementia.
Immediate vs delayed extubation after pediatric liver transplantation: a systematic review and meta-analysis.
This systematic review and meta-analysis compared immediate operating-room extubation with delayed extubation after pediatric orthotopic liver transplantation.
Fractional CO₂ laser combined with intradermal and topical platelet-rich plasma for hypertrophic scars: a randomized controlled trial.
This prospective, randomized, assessor-blinded trial compared fractional CO₂ laser plus intradermal and topical platelet-rich plasma (PRP) with laser plus saline in 120 patients with hypertrophic scars.
The Impact of Telemedicine Interventions on Maternal and Fetal Outcomes in Women With Gestational Diabetes: Systematic Review and Meta-Analysis of Randomized Controlled Trials.
This systematic review and meta-analysis pooled 23 randomized controlled trials involving 3055 women with gestational diabetes to assess telemedicine and maternal and fetal outcomes.
Prophylactic neurectomy versus nerve preservation in open inguinal hernia repair for prevention of chronic postoperative inguinal pain (CPIP): a systematic review and meta-analysis.
This systematic review and meta-analysis assessed prophylactic neurectomy versus nerve preservation in adults undergoing elective open anterior inguinal hernia repair, including 17 randomized trials.
Protective effect of N-acetylcysteine on oxaliplatin-induced peripheral neuropathy in colorectal cancer: a randomized controlled trial.
This randomized controlled trial evaluated oral N-acetylcysteine (NAC) for preventing oxaliplatin-induced peripheral neuropathy in 46 patients with stage III or high-risk stage II colorectal cancer receiving adjuvant…
The perceptions of hematopoietic stem cell transplantation decision-making in patients with hematologic malignancies: a qualitative systematic review.
This qualitative systematic review synthesized research on how patients with hematologic malignancies perceive decisions about hematopoietic stem cell transplantation (HSCT).
Lesion Water Content on CT Predicts 12-Month Outcome and Modifies Thrombectomy Effect in Large-Core Stroke-A Secondary Analysis of the TENSION Trial.
This secondary analysis of the randomized TENSION trial examined whether CT-derived net water uptake (NWU) predicts 12-month outcomes and modifies thrombectomy effects in 198 patients with large-core ischemic stroke.
Gut virome remodeling after fecal microbiota transplantation is associated with virus-bacteria co-variation and metabolic response in obesity and type 2 diabetes.
This randomized controlled trial examined longitudinal fecal virome and bacteriome changes after fecal microbiota transplantation (FMT) in people with obesity and type 2 diabetes.
Search for the glycated hemoglobin target minimizing mortality among people with type 2 diabetes with rare incidence of treatment-related severe hypoglycemia - Epidemiologic analysis of J-DOIT3 randomized controlled trial.
This landmark analysis of the J-DOIT3 randomized controlled trial examined associations between updated HbA1c and cardiovascular outcomes or mortality among people with type 2 diabetes, in a setting where severe…
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