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1293 articles
October 202624
A Systematic Review and Meta-Analysis of Randomized Clinical Trials Comparing the Effectiveness of Corticosteroid Injection Versus Night Splints in Patients With Carpal Tunnel Syndrome.
This systematic review and meta-analysis of randomized controlled trials compared corticosteroid injection (CSI) with night splinting (NS) for carpal tunnel syndrome.
Curative-intent management of de novo metastatic nasopharyngeal carcinoma: an evidence-based consensus guideline from the International Collaborating Oncology Organisations.
This international consensus guideline addresses curative-intent management of de novo metastatic nasopharyngeal carcinoma, a population historically treated with palliative intent.
Effects of a Multicomponent App-Based Exercise Program on Motor Skill Development in Children With Attention Deficit Hyperactivity Disorder: A Secondary Outcome Analysis of a Three-Arm Randomized Controlled Trial.
This secondary outcome analysis of a three-arm randomized controlled trial assessed motor skills in 145 children aged 6–10 years with ADHD.
Effects of Walnut Consumption on Inflammatory Cytokines and Adipokines in Adults: A Systematic Review and Dose-Response Meta-Analysis.
This systematic review and dose-response meta-analysis assessed randomized trials of walnut intake and inflammatory cytokines and adipokines in adults.
From Daily Attitudes to Alcohol-Related Harm: A Within-Person Serial Mediation Test Informed by the Theory of Planned Behavior.
This multilevel daily-diary study examined whether day-to-day changes in attitudes toward heavy drinking were linked to alcohol-related harm through intentions and consumption.
The Effects of Mind-Body Exercise on Cognitive Function and Peripheral Blood BDNF in Elderly People With Mild Cognitive Impairment: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis pooled 17 randomized controlled trials involving 1,251 older adults with mild cognitive impairment to assess mind-body exercise and cognition and peripheral blood BDNF.
Prehospital Analgesia in Trauma: A Systematic Review of Current Evidence.
This systematic review assessed the safety and effectiveness of pharmacologic analgesia given before hospital arrival to acutely injured adults aged over 15 years.
Effectiveness of a Ceramide-Based Lamellar Emulsion on Skin Barrier Function in Surgical Nurses: A Randomized Controlled Trial.
This single-center randomized controlled trial assessed whether a ceramide-based lamellar emulsion improved hand skin barrier function in surgical nurses exposed to frequent perioperative hand hygiene.
A pilot study of electromagnetic therapy versus biofeedback-based pelvic floor muscle training for pelvic organ prolapse: A mixed-methods approach.
This mixed-methods pilot randomised trial compared high-intensity focused electromagnetic (HIFEM) therapy, supervised pelvic floor muscle training (PFMT) with biofeedback and/or electrostimulation, and usual care in…
Efficacy of High-Frequency Transcranial Magnetic Stimulation Therapy for Depression With Insomnia Symptoms: A Systematic Review and Meta-Analysis Based on Randomized Controlled Trials.
This systematic review and meta-analysis of randomized controlled trials assessed left dorsolateral prefrontal cortex-targeted high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) for people with…
The Effect of Using Heated IV Fluids With Underbody Warmers on Maternal and Neonatal Well-Being in Cesarean Delivery Operations: A Randomized Clinical Trial.
This randomized clinical trial at a university hospital compared underbody warming alone, underbody warming plus heated IV fluids, and passive blanket heating in 105 pregnant patients undergoing cesarean delivery.
Patient-reported outcome measures for depressive symptoms in adults with spinal cord injury: a COSMIN systematic review.
This COSMIN systematic review assessed patient-reported measures of depressive symptoms in adults with traumatic or non-traumatic spinal cord injury.
Effect of vutrisiran on components of health status in transthyretin amyloidosis with cardiomyopathy: the HELIOS-B study.
This analysis of HELIOS-B, a double-blind, randomized, placebo-controlled trial, examined individual health-status components in patients with transthyretin amyloidosis with cardiomyopathy (ATTR-CM).
Postoperative membranous urethral length and continence recovery after robot-assisted radical prostatectomy: a Bayesian longitudinal meta-analysis.
This PROSPERO-registered systematic review and Bayesian longitudinal meta-analysis examined whether postoperative MRI-measured membranous urethral length (MUL) was associated with urinary continence recovery after…
Mitral regurgitation in patients with heart failure and reduced ejection fraction: insights from GALACTIC-HF.
This analysis of the randomized, multicentre GALACTIC-HF trial examined mitral regurgitation (MR) and outcomes in patients with heart failure and reduced ejection fraction.
Association between chronic opioid exposure and cardiovascular disease: a systematic review and meta-analysis.
This systematic review and meta-analysis examined associations between chronic opioid exposure—including opium use, opioid use disorder, and prescription opioids—and cardiovascular disease in human studies.
Ergonomic interventions for treating work-related complaints of the arm, neck or shoulder in adults.
This Cochrane systematic review and meta-analysis assessed ergonomic interventions for work-related arm, neck or shoulder complaints (CANS) in adults.
Proof-of-Concept Phase 2a Trial of VH4524184: An Emerging Third-Generation Integrase Strand Transfer Inhibitor With an Enhanced Resistance Profile.
This randomized, double-blind, placebo-controlled phase 2a trial assessed short-course oral VH-184 monotherapy in adults with HIV-1 who were antiretroviral-therapy naive and had HIV-1 RNA ≥ 3000 copies/mL.
Performance of prediction models for incident heart failure and heart failure hospitalization in individuals with type 2 diabetes: a systematic review and meta-analysis.
This systematic review and Bayesian meta-analysis assessed multivariable models predicting incident heart failure (HF) or HF hospitalization (HFH) in people with type 2 diabetes.
Pars plana vitrectomy with silicone oil versus pars plana vitrectomy alone for postoperative endophthalmitis: A randomized controlled trial.
This prospective randomized controlled trial compared pars plana vitrectomy (PPV) with 1000-cSt silicone oil (SO) tamponade against PPV alone in 40 eyes with severe post-phacoemulsification endophthalmitis unresponsive…
Vascular health after quitting smoking or switching to e-cigarette use: a systematic review of prospective studies with GRADE assessment.
This systematic review assessed prospective evidence on vascular function after smoking cessation or switching to exclusive e-cigarette use among adult smokers.
Long-term impact of aficamten on patient-reported outcome measures in obstructive hypertrophic cardiomyopathy: results from FOREST-HCM.
This open-label extension study assessed longer-term patient-reported outcomes with aficamten in people with obstructive hypertrophic cardiomyopathy who had completed an aficamten trial.
Immunogenicity and Safety of Coadministration of AS01E-Adjuvanted Respiratory Syncytial Virus Prefusion F Protein Vaccine and a COVID-19 mRNA Vaccine in Adult s Aged ≥50 Years: A Phase 3, Randomized, Noninferiority Trial.
This phase 3, open-label, multicenter randomized noninferiority trial compared coadministration of an AS01E-adjuvanted RSV prefusion F vaccine and an Omicron XBB.1.5 COVID-19 mRNA vaccine with administration…
Impact of Intermittent Preventive Treatment for Malaria in Pregnancy With Sulfadoxine-Pyrimethamine, Dihydroartemisinin-Piperaquine, and Their Combination on Infant Outcomes: A Randomized Controlled Trial.
This double-blind randomized controlled trial compared infant malaria and growth outcomes after maternal intermittent preventive treatment in pregnancy with sulfadoxine-pyrimethamine (SP), dihydroartemisinin-piperaquine…
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