Trending archive
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1007 articles
October 202624
Berberine improves diabetic foot ulcer healing after tibial transverse osteotomy by inhibiting the PDGF-B/PDGFRβ signaling pathway .
This prospective, single-centre, randomized, placebo-controlled trial evaluated local berberine injections added to tibial transverse osteotomy (TTO) in patients with Wagner grade 2–4 diabetic foot ulcers.
Efficacy and safety study of diclofenac epolamine topical patch in accelerating rehabilitation of moderate hamstring strain: A randomized controlled trial .
This single-centre, double-blind, placebo-controlled randomised trial evaluated topical diclofenac epolamine alongside rehabilitation in 120 patients with moderate hamstring strain.
A Short Evidence-Based, Belief-Focused Educational Video Improves Back Pain Beliefs but Not Lifting Behaviour in Healthy Office Workers: An Exploratory Randomised Controlled Trial.
This assessor-blind exploratory randomised controlled trial assigned 50 healthy office workers to a brief video about back pain beliefs and management or an anatomy-video control.
From Bench to Bedside: Evaluating the Accuracy of Clinical Sensory Testing in Detecting Somatosensory Disorders. A Systematic Review.
This systematic review assessed the diagnostic accuracy of clinical sensory tests (CSTs) for somatosensory disorders across populations and conditions, comparing test results with reference standards.
Local Delivery of Interferon-β1a for Respiratory Viral Infections: A Systematic Review.
This PRISMA-guided systematic review assessed locally delivered intranasal or inhaled interferon-β1a for respiratory viral infections, covering clinical trials and experimental evidence.
Consequences of opioid exposure in disease-free cancer survivors: A systematic literature review.
This systematic literature review examined the consequences of persistent opioid exposure after curative-intent treatment in disease-free cancer survivors.
Effectiveness of Exercise Snacks in Mitigating Adolescent Problematic Smartphone Use: A Four-Wave Cluster Randomized Controlled Trial.
This four-wave cluster randomized controlled trial tested whether brief, vigorous activity breaks could reduce problematic smartphone use among 386 adolescents in 12 secondary-school classes.
Fertility Treatment and Risk of Melanoma: A Certainty-Rated Systematic Review and Meta-Analysis of 3,733,499 Women.
This certainty-rated systematic review and random-effects meta-analysis examined observational evidence on fertility treatment and incident melanoma in women.
Dyspnea Reduction With L-Menthol Inhalation Improves High-Intensity Endurance Running Performance in Healthy Trained Adults.
This randomized, counterbalanced crossover trial tested whether L-menthol inhalation reduces breathlessness and improves high-intensity running performance in 18 trained endurance runners with normal spirometry.
An Individual Meta-Analysis of Psychological Treatments for Mood and Personality Disorders Using the Severity Diagnostic System of ICD-11.
This individual patient meta-analysis examined whether ICD-11 personality-disorder severity was associated with short-term outcomes in 1,384 patients from four randomised trials of psychological treatments, mainly…
Safety of low lipoprotein(a) levels: the FOURIER trial.
This analysis of the randomized, multicentre FOURIER trial examined associations between lipoprotein(a) [Lp(a)] levels and safety outcomes in patients with stable atherosclerotic cardiovascular disease receiving…
Interleukin-6 and C-reactive protein prognostic value following acute coronary syndrome.
This post hoc prognostic analysis of the multicentre ODYSSEY OUTCOMES randomised trial examined hsCRP and IL-6 in 11,817 patients with recent acute coronary syndrome.
Measurement Properties of Hand-Held Dynamometry for Ankle Strength Assessment: A COSMIN-Based Systematic Review and Meta-Analysis.
This COSMIN-based systematic review and meta-analysis assessed handheld dynamometry (HHD) for measuring isometric ankle muscle strength in healthy individuals.
Prognostic associations between patient-reported outcomes and progression-free and overall survival in advanced gastric or gastroesophageal junction adenocarcinoma with PD-L1 TAP score ≥ 5%: results from the RATIONALE-305 trial.
This analysis of the randomised RATIONALE-305 trial examined whether longitudinal patient-reported outcomes (PROs) were associated with progression-free survival (PFS) and overall survival (OS) in patients with advanced…
A randomized study comparing plant sterol- and soluble fiber-enriched soymilk with plain soymilk in adults with elevated LDL cholesterol.
This randomized controlled trial compared plant sterol- and soluble fiber-enriched soymilk with plain soymilk in 242 adults with hypercholesterolemia, untreated or on stable lipid-lowering therapy.
Reduced-dose alternate-day oral iron supplementation in women with iron deficiency: a randomized controlled trial.
This 42-day, randomized, parallel-group active-controlled trial compared two oral iron regimens in 66 women aged 18–50 years with iron deficiency (serum ferritin < 30 ng/mL).
Digital Therapeutic Interventions for Suicide Prevention: A Systematic Review and Meta-Analysis of Their Effectiveness in Reducing Suicidal Ideation and Suicide Attempts.
This systematic review and meta-analysis synthesised randomized clinical trials of digital interventions for suicide prevention. Seventeen studies (N = 5.089) were included.
Informal Caregiver-Observed Fall Risk Indicators and Caregiver Responses to Prevent Falls Among Community-Dwelling Older People: A Systematic Review.
This systematic review synthesized 16 studies of informal caregivers’ observations of fall-risk indicators and their preventive responses among community-dwelling older people.
Effect of Rapid Rollover on Pneumothorax Rate After Percutaneous CT-Guided Lung Biopsy: A Multisite Randomized Controlled Trial Within a Single Health System.
This prospective, multisite randomized controlled trial evaluated rapid rollover after CT-guided lung biopsy using an anterior or lateral approach.
Stereotactic body radiation therapy for pancreatic cancer: evaluating its efficacy, safety, and future prospects: systematic review.
This systematic narrative review assessed stereotactic body radiation therapy (SBRT) for locally advanced pancreatic cancer, including patients unsuitable for surgery.
Cine Magnetic Resonance Imaging for Assessing Chest Wall Invasion in Lung Cancer: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated cine MRI for detecting chest wall invasion in lung cancer, using surgical and histopathologic findings as the reference standard.
Influence of capsular tension ring implantation on dynamic in vivo capsular apposition and intraocular lens behavior in highly myopic eyes.
This prospective randomized clinical trial assessed whether capsular tension ring (CTR) implantation affects capsular apposition and intraocular lens (IOL) behavior after cataract surgery in highly myopic eyes.
Efficacy and safety of mitapivat in patients with sickle cell disease (RISE UP): a phase 3, double-blind, global, randomised, placebo-controlled trial.
RISE UP was a phase 3, double-blind, global, randomised, placebo-controlled trial conducted at 69 sites in 15 countries. It evaluated twice-daily mitapivat in patients older than 16 years with sickle cell disease…
Uniportal versus multiportal robotic-assisted thoracic surgery for anatomical pulmonary resection: a systematic review and meta-analysis of perioperative recovery and surgical quality.
This systematic review and meta-analysis compared uniportal/single-port with multiportal robotic-assisted thoracic surgery for anatomical pulmonary resection.
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