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909 articles
October 202624
Heterogeneity in Depression and Suicidality Risk Among Vitiligo Patients: A Meta-Analysis of Adolescent Complexity and Subgroup Stratification.
This meta-analysis assessed depression and suicidality in people with vitiligo, drawing on 73 studies identified through searches of four databases. The pooled prevalence of depression was 0.37 (95% CI, 0.30-0.45).
The Effects of Virtual Reality Group Reminiscence Therapy on Agitation, Cognition, Depression and Social Function in Patients With Alzheimer's Disease.
This assessor-blinded randomised controlled trial evaluated multisensory virtual reality group reminiscence therapy in 60 people with Alzheimer’s disease, comparing twice-weekly 40-minute sessions for 8 weeks with…
Decitabine plus busulfan-cyclophosphamide versus busulfan-cyclophosphamide myeloablative conditioning before allogeneic haematopoietic stem cell transplantation for reducing risk of relapse in adult KMT2A‑rearranged leukaemia in China: an open-label, multicentre, randomised phase 3 trial.
This open-label, multicentre, randomised phase 3 trial compared decitabine plus busulfan-cyclophosphamide (DAC-BuCy) with BuCy conditioning before allogeneic HSCT in 130 patients aged 14–65 years with KMT2A-rearranged…
The Effect of Bupropion in Peripheral Neuropathic Pain A Randomized, Double-Blind, Placebo-Controlled Study.
This randomized, double-blind, placebo-controlled crossover study assessed bupropion for peripheral neuropathic pain and whether response varied with conditioned pain modulation (CPM) or sensory phenotype.
The Effects of Force-Velocity Profile-Based Load Prescription on Muscle Power and Functional Performance in Velocity-Deficient Older Adults.
This 12-week randomized controlled trial compared force–velocity profile-guided resistance-training loads in adults aged 65 years or older with a velocity deficit.
Between Skin and Brain: A Systematic Review of 712 Cases 1976-2025 Reveals a Highly Diverse Disease Spectrum in Chaetothyriales.
This systematic review examined the global epidemiology, causative species, clinical presentations, and outcomes of 712 reported Chaetothyriales infections from 1976 to 2025.
Virtual Social Interaction and Psychological Capital in Chemotherapy Patients: A Randomized Controlled Trial.
This single-blind randomized controlled trial evaluated a six-week virtual social interaction program for 76 patients receiving chemotherapy at one Iranian hospital.
Effectiveness of Tomazoni Measurement Method for Central Catheter Tip Positioning in Neonates: A Randomised Controlled Trial.
This pragmatic, parallel-group randomised controlled trial compared the Tomazoni and traditional measurement methods for positioning peripherally inserted central catheter (PICC) tips in neonates at a Brazilian neonatal…
Incidence of Intensive Care Unit Delirium After Heart Surgery: A Feasibility Study of a Forest Environment Intervention.
This randomized feasibility study evaluated forest-environment and light-exposure interventions, compared with standard care, in adults undergoing elective cardiac surgery at a tertiary ICU in Austria.
Artificial Intelligence-Enabled Electrocardiogram Screening for Detection of Low Ejection Fraction in Routine Care: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
This systematic review and meta-analysis evaluated randomised controlled trials of AI-enabled ECG screening for low ejection fraction in adults without known heart failure undergoing routine ECGs.
Phase 1 Study of Safety and PK With A Combination of Omeprazole and Trimetazidine for Fatty Acid Oxidation Inhibition in Patients With Advanced Solid Tumors.
This Phase I, open-label, 3 + 3 dose-escalation study assessed safety, tolerability, pharmacokinetics, and preliminary antitumor activity of once-daily oral omeprazole plus trimetazidine, two fatty acid oxidation…
Reducing Central Line-Associated Bloodstream Infections in ICUs: A Systematic Review of Barriers and Facilitators and Intervention Measures.
This PRISMA-guided systematic review examined barriers and facilitators to implementing central line-associated bloodstream infection (CLABSI) prevention among ICU healthcare workers.
Prone positioning and high-frequency oscillatory ventilation in early paediatric acute respiratory distress syndrome (PROSpect): an international, two-by-two factorial, response-adaptive, phase 3, randomised controlled trial.
PROSpect was an international, two-by-two factorial, phase 3 randomised controlled trial comparing prone with supine positioning and high-frequency oscillatory ventilation (HFOV) with conventional mechanical ventilation…
Post-transplant follow-up for kidney transplant recipients: a systematic review of clinical practice guidelines.
This systematic review compared clinical practice guidelines for post-transplant follow-up of kidney transplant recipients, assessing methodological quality and recommendations for surveillance.
Effects of a telehealth-supported home-based exercise program on functional capacity, sarcopenia risk, and patient-reported outcomes in non-dialysis stage 4-5 chronic kidney disease.
This prospective, parallel-group randomized controlled trial assessed a 12-week telehealth-supported home exercise program in adults aged ≥45 years with non-dialysis stage 4-5 chronic kidney disease.
Association of Helicobacter pylori eradication with proteinuria reduction and kidney outcomes: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed whether Helicobacter pylori eradication is associated with renal benefits in people with kidney disease or proteinuria.
Prehospital Analgesia in Trauma: A Systematic Review of Current Evidence.
This systematic review assessed the safety and effectiveness of pharmacologic analgesia given before hospital arrival to acutely injured adults aged over 15 years.
A Systematic Review and Meta-Analysis of Randomized Clinical Trials Comparing the Effectiveness of Corticosteroid Injection Versus Night Splints in Patients With Carpal Tunnel Syndrome.
This systematic review and meta-analysis of randomized controlled trials compared corticosteroid injection (CSI) with night splinting (NS) for carpal tunnel syndrome.
Effects of Walnut Consumption on Inflammatory Cytokines and Adipokines in Adults: A Systematic Review and Dose-Response Meta-Analysis.
This systematic review and dose-response meta-analysis assessed randomized trials of walnut intake and inflammatory cytokines and adipokines in adults.
A pilot study of electromagnetic therapy versus biofeedback-based pelvic floor muscle training for pelvic organ prolapse: A mixed-methods approach.
This mixed-methods pilot randomised trial compared high-intensity focused electromagnetic (HIFEM) therapy, supervised pelvic floor muscle training (PFMT) with biofeedback and/or electrostimulation, and usual care in…
The Effects of Mind-Body Exercise on Cognitive Function and Peripheral Blood BDNF in Elderly People With Mild Cognitive Impairment: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis pooled 17 randomized controlled trials involving 1,251 older adults with mild cognitive impairment to assess mind-body exercise and cognition and peripheral blood BDNF.
The Effect of Using Heated IV Fluids With Underbody Warmers on Maternal and Neonatal Well-Being in Cesarean Delivery Operations: A Randomized Clinical Trial.
This randomized clinical trial at a university hospital compared underbody warming alone, underbody warming plus heated IV fluids, and passive blanket heating in 105 pregnant patients undergoing cesarean delivery.
Effectiveness of a Ceramide-Based Lamellar Emulsion on Skin Barrier Function in Surgical Nurses: A Randomized Controlled Trial.
This single-center randomized controlled trial assessed whether a ceramide-based lamellar emulsion improved hand skin barrier function in surgical nurses exposed to frequent perioperative hand hygiene.
Effects of a Multicomponent App-Based Exercise Program on Motor Skill Development in Children With Attention Deficit Hyperactivity Disorder: A Secondary Outcome Analysis of a Three-Arm Randomized Controlled Trial.
This secondary outcome analysis of a three-arm randomized controlled trial assessed motor skills in 145 children aged 6–10 years with ADHD.
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