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1316 articles

October 202624

Clinical ResearchCardiology

Global Prevalence of Adherence to Antihypertensives and Associated Moderating Factors Among Adults With Hypertension: A Meta-Analysis.

This systematic review and meta-analysis estimated global adherence to antihypertensive medication among adults with hypertension.

J Am Heart AssocOct 16, 2026Read summary
Clinical ResearchPsychiatry

Moxibustion for depression: A meta-analysis.

This meta-analysis assessed moxibustion, alone or alongside other therapies, for depression. It included 15 randomized controlled trials with 1510 patients, comparing moxibustion with sham treatment, no treatment, or…

Medicine (Baltimore)Oct 16, 2026Read summary
Clinical ResearchDermatology

Hyaluronic acid-based skin booster with glutathione combined with 1064-nm Nd:YAG laser and oral tranexamic acid for melasma: A prospective comparative study.

This randomized comparative study evaluated whether intradermal hyaluronic acid-based glutathione (HA-GSH) improves outcomes when added to low-fluence 1064-nm Q-switched Nd:YAG laser and oral tranexamic acid in Chinese…

Medicine (Baltimore)Oct 16, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

Safety and efficacy of a novel miniaturized robotic assisted surgery system in hysterectomy: a prospective, investigational device exemption clinical trial.

This prospective, multicentre, non-randomised Investigational Device Exemption trial assessed the safety and effectiveness of the MIRA miniaturized robotic system for benign hysterectomy.

J Robot SurgOct 16, 2026Read summary
Clinical ResearchCardiology

Effectiveness of Discrete Strategies and Implementation Bundles for Improving Clinician Prescription of Clinical Practice Guideline-Recommended Medications for Atherosclerotic Occlusive Disease: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed randomized trials of strategies to improve prescription of guideline-strongly-recommended medications for adults with atherosclerotic occlusive disease.

J Am Heart AssocOct 16, 2026Read summary
Clinical ResearchGeriatrics

Effectiveness of traditional mind-body exercises on fall risk test scores and balance in older adults: A systematic review and meta-analysis.

This systematic review and meta-analysis pooled 31 randomized controlled trials involving 3,622 older adults to assess traditional mind-body exercises and fall-risk test scores and balance.

Medicine (Baltimore)Oct 16, 2026Read summary
Clinical ResearchEndocrinology

Efficacy and safety of imeglimin hydrochloride for metabolic dysfunction-associated steatotic liver disease with type 2 diabetes: Single-center, single-arm phase 2 (IMELD study).

This single-center, single-arm phase 2 interventional study assessed 24 weeks of imeglimin in patients with metabolic dysfunction-associated steatotic liver disease (MASLD) and type 2 diabetes.

Medicine (Baltimore)Oct 16, 2026Read summary
Clinical ResearchAnesthesiology

Nociception Level-Guided Multimodal Analgesia with External Oblique Intercostal Plane Block in Laparoscopic Cholecystectomy.

This double-blind randomized controlled trial compared nociception level (NOL)-guided multimodal analgesia (MMA) incorporating an external oblique intercostal plane (EOIP) block with intravenous dexketoprofen alone in…

J Vis ExpOct 16, 2026Read summary
Clinical ResearchHematology

Denecimig (Mim8) prophylaxis once every 2 weeks for hemophilia A with or without inhibitors: 26-week results from FRONTIER4.

This open-label extension study evaluated every-2-week (Q2W) denecimig prophylaxis in patients aged ≥12 years with hemophilia A, with or without inhibitors, who had previously received denecimig in a phase 2 study and…

Blood AdvOct 16, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Effects of blood flow restriction training in adult upper-limb musculoskeletal rehabilitation: A systematic review.

This systematic review assessed the clinical effects, tolerability, and prescription of blood flow restriction training (BFRT) in adults undergoing rehabilitation for upper-limb musculoskeletal conditions.

Medicine (Baltimore)Oct 16, 2026Read summary
Clinical ResearchOrthopedic Surgery

Effectiveness of kinesio tape in the treatment of patients with plantar fasciitis: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed kinesio tape (KT) for plantar fasciitis, including 16 randomized controlled trials.

Medicine (Baltimore)Oct 16, 2026Read summary
Clinical ResearchGeriatrics

Participant Characteristics Associated With Loneliness Reduction During a Digital Social Robot Intervention Among Older Adults Living Alone in Japan: Secondary Analysis of a Randomized Controlled Trial.

This secondary analysis of a randomized controlled trial examined whether participant characteristics were associated with changes in loneliness during a digital social robot intervention among community-dwelling older…

J Med Internet ResOct 16, 2026Read summary
Clinical ResearchOrthopedic Surgery

Artificial intelligence empowering the diagnosis and treatment of rotator cuff tears: A systematic review from image optimization to prognosis prediction.

This systematic review examined original studies applying artificial intelligence across the rotator cuff tear care pathway, including imaging, diagnosis, anatomical measurement, and prognosis.

Medicine (Baltimore)Oct 16, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Kinematic adaptations of the uppercut punch following an eight-week biomechanics-based training intervention in amateur boxers.

This randomized controlled trial examined whether an eight-week biomechanics-based program changed right-hand uppercut mechanics in 24 male amateur boxers with 3–4 years of training experience.

Acta Bioeng BiomechOct 16, 2026Read summary
Clinical ResearchPediatrics

Sleep apnea-hypopnea in children: Evidence that Lize Tongqi decoction with acupuncture, moxibustion, and Xinwu acupoint stimulation is superior to standard Western treatment using montelucast/mometasone furoate.

This randomized controlled trial compared a combined traditional Chinese medicine and acupuncture-based regimen with montelukast plus mometasone in 60 children with snoring (mean age 7.9 years).

Int J Clin Pharmacol TherOct 16, 2026Read summary
Clinical ResearchPsychiatryOpen access

Infant hippocampal and amygdala volume in an observational follow-up from a randomized clinical trial for maternal prenatal depression.

This observational follow-up examined brain volumes and later negative emotionality in 109 infants born to mothers who had participated in a randomized clinical trial of brief interpersonal psychotherapy for prenatal…

Nat CommunOct 16, 2026Read summary
Clinical ResearchEndocrinology

Bone phenotype of patients with genetic forms of lipodystrophy: a systematic review of literature.

This systematic review examined bone manifestations in people with genetic lipodystrophies, using human studies identified through searches of PubMed, EMBASE, and the Cochrane Library.

J Clin Endocrinol MetabOct 16, 2026Read summary
Clinical ResearchCardiology

Artificial intelligence-enhanced electrocardiography for predicting mortality and major adverse cardiovascular events: A systematic review and narrative synthesis.

This systematic review and narrative synthesis evaluated AI-enabled 12-lead or single-lead ECG models for predicting all-cause mortality, cardiovascular mortality, and major adverse cardiovascular events in adults.

PLoS OneOct 16, 2026Read summary
Clinical ResearchNeurologyOpen access

Tenecteplase, alteplase, and endovascular thrombectomy in extended-window acute ischemic stroke with intracranial large-vessel occlusion: a Bayesian network meta-analysis.

This Bayesian network meta-analysis compared reperfusion strategies in imaging-selected patients with acute ischemic stroke treated 4.5 to 24 hours after onset or last known well.

J NeurolOct 16, 2026Read summary
Clinical ResearchRheumatology

Additive effects of active vitamin D3 or vitamin E administration on therapeutic lower-limb home exercise for knee osteoarthritis: A pilot prospective randomized controlled trial.

This pilot prospective randomized controlled trial assessed whether active vitamin D3 or vitamin E added benefit to home exercise in postmenopausal women with symptomatic knee osteoarthritis.

Medicine (Baltimore)Oct 16, 2026Read summary
Clinical ResearchCardiology

Psychological Stress and the Diurnal Patterns of Sodium Excretion and Blood Pressure: Results From the SABRE Study.

The SABRE study examined whether urinary sodium responses to mental stress were associated with day–night sodium excretion patterns and systolic blood pressure (BP) dipping in apparently healthy adults.

J Am Heart AssocOct 16, 2026Read summary
Clinical ResearchUrologyOpen access

Preoperative ureteral rest and outcomes of robot-assisted upper urinary tract reconstruction: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed whether preoperative ureteral rest is associated with outcomes after robot-assisted ureteral reconstruction or pyeloplasty.

J Robot SurgOct 16, 2026Read summary
Clinical ResearchPathology (Anatomic & Clinical)Open access

SOX10 Expression in Primary Salivary Gland Tumors: A Meta-Analysis.

This PRISMA-guided systematic review and meta-analysis assessed SOX10 immunohistochemical expression across primary salivary gland tumors. It included 35 studies comprising 1146 histological and 35 cytological samples.

Head Neck PatholOct 16, 2026Read summary
Clinical ResearchCardiology

Dapagliflozin After Transcatheter Aortic Valve Implantation According to Frailty in DapaTAVI Trial.

This post hoc analysis of the multicenter randomized DapaTAVI trial examined whether frailty modified dapagliflozin’s effects after transcatheter aortic valve implantation.

J Am Heart AssocOct 16, 2026Read summary

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