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360 articles
March 20263
Acute Kidney Injury and Extreme Rhabdomyolysis due to Carnitine Palmitoyltransferase II Deficiency: A Case Report.
A 47-year-old man presented with influenza-like symptoms and rapidly developed extreme rhabdomyolysis, with creatine kinase >126,800 IU/L, dark urine, metabolic acidosis, multiorgan dysfunction, and acute kidney injury…
High-Flow Nasal Oxygen and the Risk of Gastric Insufflation: A Systematic Review and Meta-Analysis Supplemented by Narrative Synthesis.
High-flow nasal oxygen (HFNO) generates positive airway pressure, raising concerns about gastric insufflation and aspiration risk.
Endovascular treatment for basilar artery occlusion: A Bayesian network meta-analysis comparing time-to-treatment windows and medical management.
This Bayesian random-effects network meta-analysis compared endovascular treatment (EVT) with best medical therapy (BMT) for basilar artery occlusion, examining treatment within 0–6 hours and beyond 6 hours.
February 20269
General Versus Non-General Anesthesia in Endovascular Treatment for Posterior Circulation Stroke: a Systematic Review and Meta-analysis.
This systematic review and meta-analysis compared general anesthesia (GA) with non-general anesthesia during endovascular therapy for posterior circulation stroke. Fourteen comparative studies included 3,899 patients.
Endovascular treatment in acute ischemic stroke patients with pre-stroke disability: A systematic review and meta-analysis.
This systematic review and meta-analysis compared endovascular thrombectomy (EVT) with best medical treatment in acute ischemic stroke patients with pre-stroke disability (mRS 2–4). Five studies included 1,400 patients.
Comparative efficacy of prehospital resuscitation strategies on mortality for patients with major trauma: a network meta-analysis.
This network meta-analysis of randomized controlled trials compared prehospital blood and non-blood resuscitation strategies in patients with major trauma.
Subcutaneous and Orbital Emphysema With Pneumocephalus Secondary to Compressed-Air Gun Injury to the Face.
A healthy 26-year-old man presented with right periorbital swelling and headache after compressed air struck his face while he was cleaning work clothes with an air gun.
Sex differences in the clinical and surgical management after intracerebral hemorrhage: A post hoc analysis of the INTERACT3 clinical trial.
This post hoc analysis of the international, stepped-wedge cluster-randomised INTERACT3 trial examined sex differences in acute clinical and surgical care among 7,036 adults with intracerebral hemorrhage; 36% were…
Effect of Bystander CPR on Survival After Out-of-Hospital Cardiac Arrest: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined the association between bystander CPR and survival after out-of-hospital cardiac arrest (OHCA), pooling observational studies comparing patients who did and did not…
Rapidly Progressive Necrotizing Soft Tissue Infection of the Chest Wall After Skeletal Muscle Injury in a Healthy Young Adult Leading to Death: A Case Report.
A previously healthy 28-year-old man presented with right shoulder and chest wall pain and was initially diagnosed with muscle strains on MRI.
Is Carbon Monoxide Poisoning a Potential Trigger for Spontaneous Coronary Artery Dissection? A Case Report and Review of the Literature.
A 55-year-old woman developed altered mental status and respiratory failure after acute carbon monoxide poisoning from a domestic gas leak and received hyperbaric oxygen therapy.
Cytotoxic Lesion of the Corpus Callosum in a Patient with Acute-on-chronic Lithium Toxicity.
A 30-year-old woman with bipolar disorder developed impaired consciousness and myoclonus while taking lithium regularly. MRI showed a hyperintense lesion in the splenium of the corpus callosum, consistent with a…
January 20269
Prevalence and incidence of post-intensive care syndrome among intensive care unit survivors: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis examined post-intensive care syndrome (PICS) among intensive care unit survivors, synthesising 34 cross-sectional and cohort studies with 6230 participants.
A Randomized, Dose-Finding Study of Sphenopalatine Ganglion Block With Bupivacaine for Emergency Department Patients With Headache.
This randomized, four-arm study in two emergency departments assessed whether bupivacaine dose and unilateral versus bilateral transnasal sphenopalatine ganglion block (SPGB) affected sustained headache relief in…
Implementing an emergency nursing framework improves the quality of clinical handover: A stepped-wedge cluster randomised control trial.
This modified stepped-wedge cluster randomised controlled trial evaluated implementation of the HIRAID® emergency nursing framework across 29 Australian rural, regional and metropolitan emergency departments between…
The Mediating Role of Cognitive Function in the Relationship Between Acute High-Altitude Stress and Casualty Care Capability Following Rapid Ascent.
This multicenter, randomized, sham-controlled trial examined whether cognitive function mediates the relationship between acute high-altitude stress and casualty care capability after rapid ascent.
Presentation of Acute Pancreatitis After Initiation of Phentermine/Topiramate for Weight Loss: An Adverse Drug Event Case Report.
A 71-year-old man developed sudden mid-epigastric pain, nausea, and vomiting about 4 days after starting extended-release phentermine/topiramate for weight loss. Imaging confirmed acute pancreatitis.
Human Factors and Quantitative Data: Diverging Perspectives on ICG use in Emergency Bowel Surgery - A systematic literature review.
This systematic review examined how human factors shape interpretation of indocyanine green (ICG) fluorescence during emergency bowel surgery, comparing reported quantitative outcomes with qualitative accounts of…
Therapeutic potential of nitric oxide and its donors in hemorrhagic and ischemic stroke: a systematic review.
This systematic review examined nitric oxide (NO) and NO donors in hemorrhagic and ischemic stroke, drawing on experimental and clinical research.
Diagnostic and Surgical Challenges of Cauda Equina Syndrome in Elderly Patients with Diabetes Mellitus: A Systematic Review and Meta-Analysis of Clinical, Radiological, and Surgical Outcomes.
This systematic review and meta-analysis assessed diagnostic presentation, surgery, complications, and recovery in elderly patients with diabetes and confirmed cauda equina syndrome (CES).
Emergency department-initiated buprenorphine vs brief intervention for opioid use disorder: a systematic review and meta-analysis of clinical trials.
This systematic review and meta-analysis pooled randomized and nonrandomized clinical trials comparing emergency department (ED)-initiated buprenorphine with brief intervention, referral, or usual care for opioid use…
December 20253
Enhanced fracture detection on radiographs with AI assistance for clinicians: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed whether AI assistance improves clinicians’ detection of fractures on radiographs.
Altered Mental Status at High Altitude: Obstructive Hydrocephalus Mimicking High-Altitude Cerebral Edema (HACE).
A 29-year-old woman developed amnesia, headache, confusion, and dysarthria after rapidly ascending a 4,404 m (14,267 ft) peak.
Successful Treatment and Transport of a Prolonged Cardiac Arrest from the Antarctic Continent with Full Neurological Recovery.
A 61-year-old man collapsed at McMurdo Station in Antarctica and was found in ventricular fibrillation. After defibrillation and advanced cardiac life support, clinic staff achieved return of spontaneous circulation.
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