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1002 articles

August 202624

Clinical ResearchPediatrics

Interventions for primary pediatric tracheomalacia: A systematic review of the therapeutic landscape and evidence quality.

This systematic review evaluated interventions for primary pediatric tracheomalacia, analyzing 22 studies involving 764 participants.

Int J Pediatr OtorhinolaryngolAug 31, 2026Read summary
Case ReportPediatrics

Paediatric Hand Compartment Syndrome Secondary to Intravenous Contrast Extravasation: A Case Report.

A 9-year-old girl developed hand compartment syndrome after 50 mL of iohexol extravasation during a contrast-enhanced abdominal CT.

J Hand Surg Asian Pac VolAug 31, 2026Read case
Clinical ResearchPediatrics

Behavioral interventions for sleep problems in autistic children: A systematic review.

This systematic review evaluated the effectiveness of behavioral sleep interventions for sleep problems in autistic children under 18 years.

Sleep MedAug 29, 2026Read summary
Case ReportOtolaryngology (ENT)

Autologous cricoid graft reconstruction of complete transglottic laryngeal atresia: Case report.

A male infant with congenital high airway obstruction syndrome underwent EXIT-to-tracheostomy at 32 weeks. At three years, he was found to have complete transglottic laryngeal atresia with severe cricoid dysplasia.

Int J Pediatr OtorhinolaryngolAug 28, 2026Read case
Clinical ResearchHematology

HOPE Kids 2: Phase 3, Randomized Trial of Voxelotor in Children With SCD and Conditional Cerebral Blood Flow Velocities.

HOPE Kids 2 was a phase 3, multicenter, double-blind, placebo-controlled randomized trial of voxelotor in children aged 2 to <15 years with sickle cell disease (HbSS/HbSβ⁰) and conditional cerebral blood flow velocities…

Am J HematolAug 28, 2026Read summary
Case ReportNeurology

Child Neurology: Radiologic Evolution and Developmental Correlates in Fetal Cerebral Sinovenous Thrombosis: A Case Report.

This case report discusses two children diagnosed with fetal cerebral sinovenous thrombosis (CSVT) via fetal MRI. Serial neuroimaging revealed significant evolution in cerebrovascular pathology, including changes in…

NeurologyAug 27, 2026Read case
Case ReportPediatrics

Dyspnea in Children with Serious Illness.

Dyspnea is a common and distressing symptom in children living with serious illnesses, particularly near the end of life, and requires thoughtful, family-centered assessment and management.

J Hosp Palliat NursAug 27, 2026Read case
Clinical ResearchPediatrics

A multi-center, open-labelled, randomized controlled extended phase III non-inferiority clinical trial to evaluate the immunogenicity and tolerability of poliomyelitis vaccine (Vero cells), inactivated, Sabin strains administered with or without routine infant vaccines.

This multi-center, open-label, randomized controlled trial evaluated the immunogenicity and tolerability of inactivated poliomyelitis vaccine (sIPV) administered with or without routine infant vaccines in 1442 healthy…

VaccineAug 27, 2026Read summary
Case ReportPediatrics

Long-Term Restoration of Anticoagulant Function After Liver Transplantation for Severe Congenital Protein C Deficiency: A Single-Center Experience Involving Three Pediatric Patients.

Three pediatric patients with severe congenital protein C deficiency underwent liver transplantation, resulting in plasma protein C activity levels exceeding 64% post-surgery.

Pediatr Blood CancerAug 27, 2026Read case
Clinical ResearchInfectious DiseasesOpen access

Malaria Vaccine Rollout in Nigeria: Current Status and Challenges.

This systematic review examined implementation, awareness, acceptance, willingness to pay, and health system readiness for malaria vaccine rollout in Nigeria.

Am J Trop Med HygAug 27, 2026Read summary
Clinical ResearchOtolaryngology (ENT)

Adjunctive pillar suturing or pharyngoplasty in pediatric adenotonsillectomy for obstructive sleep apnea: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effectiveness of adjunctive pillar suturing or pharyngoplasty in pediatric adenotonsillectomy for obstructive sleep apnea (OSA).

Int J Pediatr OtorhinolaryngolAug 26, 2026Read summary
Clinical ResearchPediatricsOpen access

Safety of a quadrivalent meningococcal conjugate vaccine (MenACYW-TT) administered concomitantly with routine pediatric vaccines in healthy infants and toddlers in USA and Puerto Rico: Results from a Phase III, randomized, active-controlled study.

This Phase III randomized controlled trial evaluated the safety of the quadrivalent meningococcal conjugate vaccine MenACYW-TT in healthy infants and toddlers in the USA and Puerto Rico.

Hum Vaccin ImmunotherAug 25, 2026Read summary
Clinical ResearchPediatrics

Comparison of immunogenicity, safety, and efficacy of EVA71 vaccine in children: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the immunogenicity, safety, and efficacy of inactivated EV-A71 vaccines in children, analyzing data from five phase III RCTs involving 36,659 participants.

Expert Rev VaccinesAug 25, 2026Read summary
Case ReportPediatrics

A 6-Month-Old Infant with Episodes of Unresponsiveness.

A 6-month-old male infant presented with episodes of unresponsiveness and bluish discoloration of the lips. Through a thorough clinical evaluation, including history-taking and physical examination, a differential…

NEJM EvidAug 25, 2026Read case
Clinical ResearchOtolaryngology (ENT)

Intracapsular tonsillectomy/tonsillotomy for severe pediatric obstructive sleep apnea A PRISMA-based systematic review and exploratory meta-analytic synthesis of full-text articles.

This systematic review and meta-analysis evaluated the effectiveness and safety of intracapsular tonsillectomy/tonsillotomy combined with adenoidectomy in children with severe obstructive sleep apnea (OSA).

Int J Pediatr OtorhinolaryngolAug 25, 2026Read summary
Case ReportPediatrics

Short Pancreas in Children With Fanconi Anemia: A Report of Three Cases.

Three children with Fanconi anemia presented with a short pancreas, characterized by the absence of the pancreatic tail, identified through computed tomography.

Pediatr Blood CancerAug 25, 2026Read case
Case ReportPediatrics

Management of ketogenic diet therapy in patients with ileostomy: A report of 2 cases.

This case series discusses two pediatric patients with medication-resistant epilepsy who underwent ketogenic diet therapy (KDT) while managing ileostomies.

Nutr Clin PractAug 25, 2026Read case
Clinical ResearchPsychiatry

Cost-Effectiveness of a Child and Parent Mindfulness-Based Training Versus Medication for Childhood ADHD.

This randomized controlled trial evaluated the cost-effectiveness of family mindfulness training ('MYmind') compared to medication for childhood ADHD in 88 children.

J Atten DisordAug 24, 2026Read summary
Clinical ResearchPediatrics

Systematic review of the mutations in the active antigenic site Ø of the prefusion F protein of the Respiratory Syncytial Virus (RSV) following the implementation of monoclonal antibody prophylaxis.

This systematic review analyzed mutations in the antigenic site Ø of the RSV prefusion F protein following the introduction of the monoclonal antibody nirsevimab in children with confirmed RSV infections.

VaccineAug 22, 2026Read summary
Clinical ResearchOtolaryngology (ENT)

Caregiver-reported short-term effect and quality of life improvements after tympanostomy tube insertion in children with chronic otitis media with effusion.

This randomized controlled trial evaluated caregiver-reported outcomes following tympanostomy tube insertion (TTI) in 60 children aged 1-4 years with chronic otitis media with effusion.

Int J Pediatr OtorhinolaryngolAug 22, 2026Read summary
Clinical ResearchPediatrics

Chloral hydrate outperforms oral midazolam in facilitating venipuncture in children: A double-blind randomized trial.

This prospective, double-blind randomized trial compared oral chloral hydrate with oral midazolam for facilitating venipuncture in hospitalized children aged 1–5 years in a tertiary hospital emergency department.

InjuryAug 22, 2026Read summary
Clinical ResearchPediatrics

Neurocognitive deficits in children with polysomnographically confirmed obstructive sleep apnea: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated neurocognitive deficits in school-aged children (mean age 5-12 years) with polysomnographically confirmed obstructive sleep apnea (OSA).

Int J Pediatr OtorhinolaryngolAug 21, 2026Read summary
Clinical ResearchInfectious Diseases

Pathways of onward HIV disclosure in relationships among young people living with vertically acquired HIV receiving antiretroviral therapy: A qualitative analysis from the BREATHER Plus trial, South Africa.

This qualitative analysis from the BREATHER Plus trial explored how young people living with vertically acquired HIV in KwaZulu-Natal, South Africa, manage onward disclosure in relationships.

Glob Public HealthAug 20, 2026Read summary
Clinical ResearchPediatrics

Umbilical Cord-Derived Cell-Based Interventions for Bronchopulmonary Dysplasia and Related Complications in Preterm Infants: A Bayesian Sparse-Data Meta-Analysis.

This meta-analysis evaluated umbilical cord-derived cell-based interventions for bronchopulmonary dysplasia (BPD) in preterm infants.

Stem Cells DevAug 20, 2026Read summary

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