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1316 articles

October 202624

Clinical ResearchEndocrinology

The effect of cognitive behavioral therapy for sleep and glycemic outcomes in people with diabetes: A systematic review and meta-analysis.

This systematic review and meta-analysis pooled 10 randomised controlled trials involving 2,827 people with diabetes from four countries to assess cognitive behavioral therapy (CBT) for sleep and glycemic outcomes.

Medicine (Baltimore)Oct 9, 2026Read summary
Clinical ResearchInfectious Diseases

Self-care practices of people living with HIV and hypertension or diabetes comorbidities in low-and-middle income countries: A systematic review.

This systematic review synthesised qualitative research on self-care among people living with HIV and hypertension or diabetes in low- and middle-income countries.

PLoS OneOct 9, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Over-dispersion in malaria-schistosoma co-infection: insights from a meta-analytical approach and systematic review.

This systematic review and meta-analysis assessed malaria–schistosomiasis co-infection patterns in endemic settings, primarily in sub-Saharan Africa, and tested whether co-infections exceeded levels expected if the…

Infect Dis PovertyOct 9, 2026Read summary
Clinical ResearchInfectious Diseases

Efficacy of Tecovirimat for the Treatment of Mpox Virus Infection in Humans: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

This systematic review and meta-analysis assessed tecovirimat efficacy and safety in patients with laboratory-confirmed mpox, comparing it with placebo or standard care in randomised controlled trials.

Rev Med VirolOct 9, 2026Read summary
Clinical ResearchOncology (Medical)

Attributable fraction of cardiac disease following radiotherapy among breast cancer survivors: a systematic review and meta-analysis.

This systematic review and random-effects meta-analysis assessed the relationship between mean heart dose (MHD) from radiotherapy and cardiac disease among breast cancer survivors.

J Radiat ResOct 9, 2026Read summary
Clinical ResearchNeurology

Stakeholder Perspectives on Digital Health Technologies in Poststroke Self-Management and Rehabilitation: Systematic Review Based on the NASSS Framework.

This systematic review synthesized stakeholder perspectives on digital health technologies (DHTs) for poststroke self-management and rehabilitation, mapping findings to the NASSS framework.

JMIR Mhealth UhealthOct 9, 2026Read summary
Clinical ResearchNeurology

Low-Frequency Repetitive Transcranial Magnetic Stimulation with Sensory Arousal Nursing for Post-Stroke Dysphagia.

This single-center, randomized, assessor-blinded study evaluated low-frequency repetitive transcranial magnetic stimulation (rTMS) combined with sensory arousal nursing versus routine nursing in 160 patients with acute…

J Vis ExpOct 9, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Oral microbiome alterations in individuals with type 1 diabetes: a systematic review.

This systematic review evaluated associations between glycemic control and oral microbial findings in people with type 1 diabetes (T1DM), distinguishing targeted tests from comprehensive microbiome profiling.

Clin Oral InvestigOct 9, 2026Read summary
Clinical ResearchOphthalmology

Dexamethasone versus triamcinolone acetonide for the management of postoperative inflammation following cataract surgery: A systematic review and meta-analysis.

This systematic review and meta-analysis compared dexamethasone with triamcinolone acetonide (TCA) for postoperative inflammation in adults undergoing phacoemulsification.

Medicine (Baltimore)Oct 9, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Efficacy of Kinesio tape for central facial paralysis: A prospective, randomized sham-controlled, single-blinded clinical trial.

This prospective, randomized, single-blind, sham-controlled trial evaluated Kinesio tape (KT) as an adjunct to routine rehabilitation in 121 adults after a first stroke with central facial paralysis.

Medicine (Baltimore)Oct 9, 2026Read summary
Clinical ResearchEndocrinology

Disease-Specific Optimal Blood Glucose Control Strategies in Critically Ill Patients: Retrospective Cohort Study and Network Meta-analysis.

This study combined a retrospective MIMIC-IV cohort analysis with a frequentist network meta-analysis of randomized trials to examine glucose-control targets in critically ill patients with sepsis, cardiac disease, or…

Nurs Crit CareOct 9, 2026Read summary
Clinical ResearchInfectious Diseases

Faith-based organisations in providing HIV services within low- and middle-income countries (LMICs): a systematic review.

This systematic review assessed empirical studies of faith-based organisations (FBOs) delivering HIV services in low- and middle-income countries.

HIV Res Clin PractOct 9, 2026Read summary
Clinical ResearchPsychiatry

Rehabilitative efficacy of cognitive behavioral therapy-based intervention for chronic fatigue syndrome: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed cognitive behavioral therapy (CBT) for fatigue, physical functioning, and psychological health in people with chronic fatigue syndrome.

Medicine (Baltimore)Oct 9, 2026Read summary
Clinical ResearchOtolaryngology (ENT)

Comparison of the Efficacy of Appiani and Zuma Maneuvers in Patients with Apogeotropic Horizontal Canal Benign Paroxysmal Positional Vertigo.

This prospective randomized comparative study evaluated the Appiani and Zuma repositioning maneuvers in patients with unilateral apogeotropic horizontal canal benign paroxysmal positional vertigo.

J Int Adv OtolOct 9, 2026Read summary
Clinical ResearchRheumatologyOpen access

Effect of pre-visit computer-assisted history-taking with a structured copy-ready summary on documentation completeness in screening for inflammatory rheumatic diseases: a randomized pilot study.

This multicenter, parallel-group randomized pilot study assessed pre-visit computer-assisted history-taking (CAHT) with a structured, copy-ready summary in adults at increased risk of inflammatory rheumatic disease…

BMC Health Serv ResOct 9, 2026Read summary
Clinical ResearchPulmonologyOpen access

Measurement properties of pulmonary function measurement and patient-reported outcome measures in patients with multiple rib fracture without flail segment; validation study alongside the multicenter FixCon trial.

This multicenter validation study, conducted alongside a randomized controlled trial, assessed pulmonary function, pain, and health-related quality-of-life measures in 180 adults with multiple rib fractures without a…

Eur J Trauma Emerg SurgOct 9, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

Fragility of randomized clinical trials comparing surgical approaches for inguinal hernia repair: a systematic review.

This systematic review assessed the fragility of dichotomous findings in randomized trials comparing inguinal hernia repair approaches.

HerniaOct 9, 2026Read summary
Clinical ResearchGeneral Surgery

Chronic postsurgical pain following thyroidectomy: A systematic review and meta-analysis.

This systematic review and random-effects meta-analysis assessed chronic postsurgical pain after thyroidectomy, synthesizing 16 studies involving 1538 patients.

Medicine (Baltimore)Oct 9, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Dose-response effects of robot-assisted training on poststroke functional recovery: A systematic review and meta-analysis.

This systematic review and meta-analysis included 36 randomised controlled trials involving 1941 adults with stroke, comparing robot-assisted training (RAT), alone or with conventional rehabilitation, against…

Medicine (Baltimore)Oct 9, 2026Read summary
Clinical ResearchCardiology

Blinded withdrawal of randomized treatment with low-dose digoxin or placebo in heart failure: the DECISION trial.

This pre-specified analysis of the multicentre, randomised DECISION trial examined blinded withdrawal of long-term low-dose digoxin or placebo in patients with heart failure and reduced or mildly reduced ejection…

Eur Heart JOct 9, 2026Read summary
Clinical ResearchCardiology

Sex differences in pharmacological treatment of heart failure: a meta-analysis of randomized trials.

This systematic review and meta-analysis examined sex differences in pharmacological treatment effects across randomized heart failure trials and whether women’s representation influenced estimated efficacy.

Eur Heart JOct 9, 2026Read summary
Clinical ResearchPsychiatry

Magnitude and Moderators of Depressive Symptom Improvement in Digital Placebo Arms: Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined blinded randomised controlled trials using digital placebos as comparators and reporting PHQ-9 outcomes.

J Med Internet ResOct 9, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

Image-guided moderately hypofractionated proton beam therapy for localized prostate cancer: 5-year outcomes of a phase II trial.

This phase II clinical trial evaluated image-guided, moderately hypofractionated proton beam therapy (63 Gy RBE in 21 fractions) in 125 men with histologically confirmed localized prostate cancer (cT1c-3aN0M0).

J Radiat ResOct 9, 2026Read summary
Clinical ResearchPediatrics

Home-based, remotely supervised, high-intensity interval training and cardiorespiratory fitness in children and adolescents with post-infectious bronchiolitis obliterans: a randomised controlled trial.

This assessor-blinded, multicentre randomised controlled trial evaluated 16 weeks of home-based, real-time remotely supervised high-intensity interval training (HIIT) in children and adolescents aged 6–20 years with…

Eur Respir JOct 9, 2026Read summary

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