Trending archive
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353 articles
October 202610
Scleral perforation in a young adult with Burkitt lymphoma.
A man in his 20s with Burkitt lymphoma receiving chemotherapy was referred for lagophthalmos and left facial nerve palsy. Weeks later, he developed acute scleral perforation.
Eosinophilic angiocentric fibrosis in paediatric IgG4-related disease.
A young girl presented with a 1.5-year history of progressive bilateral upper eyelid swelling and proptosis, more pronounced on the right.
Uveitis despite adalimumab therapy in Blau syndrome.
A middle childhood boy initially diagnosed with oligoarticular juvenile idiopathic arthritis presented with persistent arthritis, recurrent fever, and skin lesions.
Microperimetry Sensitivity Changes at the Functional Transition Zone and at the EZ Margins in X-Linked Retinitis Pigmentosa Treated With Gene Therapy.
This post-hoc analysis of the randomized Skyline trial examined how photoreceptor ellipsoid-zone (EZ) structure related to microperimetry sensitivity in eyes with X-linked retinitis pigmentosa treated with gene therapy.
Genotype-Phenotype Relationships in Patients Carrying Biallelic FDXR Pathogenic Variants-New Cases and Systematic Review.
Biallelic pathogenic FDXR variations were identified in 2017 as being responsible for sensorial neuropathies. The first reported patients suffered from auditory and optic sensorineural impairments (ANOA, MIM #617717).
Presentation and management of tislelizumab induced toxic optic neuropathy.
A woman with metastatic lung adenocarcinoma developed painless, progressive bilateral visual blurring after receiving second-line treatment with gemcitabine, carboplatin, and tislelizumab.
Cicatricial Ectropion in the Setting of IL-13 Inhibition.
An 81-year-old man with extensive atopic dermatitis was treated with dupilumab, leading to significant improvement. However, he later developed ocular symptoms and inferior cicatricial ectropion of the left lower eyelid.
Identification of Variants in Two Families With Congenital Cataract by Whole Exome Sequencing.
Congenital cataract (CC) is an ophthalmic disorder diagnosed at birth or during early infancy, characterized by severe visual impairment and potential blindness.
Anterior Stromal Melt Following Implantation of a Large Size Corneal Allogenic Intrastromal Ring Segment (CAIRS).
To report delayed anterior stromal melt following corneal allogenic intrastromal ring segment (CAIRS) implantation in a patient without known systemic or ocular risk factors.
Sutureless Epikeratophakia After Small Incision Lenticule Extraction: A Case Report to Correct Corneal Deformity.
An 18-year-old woman developed severe corneal thinning, with a residual stromal bed of 176 μm, and irregular hyperopic astigmatism in her left eye after a femtosecond laser malfunction during keratorefractive lenticule…
September 202614
Clinical Reasoning: A 60-Year-Old Woman With Fever, Headache, Diplopia, and Unilateral Periorbital Swelling.
A 60-year-old woman presented with fever, headache, horizontal diplopia, and unilateral periorbital swelling after experiencing recurrent gingival swelling and pain for about a month.
The FIRE technique - A tube ligation alternative.
A patient undergoing glaucoma surgery with a nonvalved glaucoma drainage device (GDD) was treated using the Flanged Intraluminal Ripcord Element (FIRE) technique.
Autologous rotational partial thickness scleral flap - A salvage technique for late leaking blebs with scleral fistula.
Two patients with late leaking blebs complicated by scleral fistulae underwent a modified autologous rotational partial-thickness scleral flap procedure.
Uveitis as a class effect of Bruton tyrosine kinase inhibitors: ibrutinib and zanubrutinib ocular toxicity.
A man in his early 50s with Waldenström macroglobulinaemia developed posterior uveitis while on ibrutinib, characterized by vitreous and retinal infiltrates.
Autologous retinal transplant for macular hole in retinal detachment following bag-intraocular lens complex dislocation.
An elderly patient in their late 80s presented with total retinal detachment and a macular hole following pars plana vitrectomy for a dislocated capsular bag-intraocular lens complex.
Bilateral Vortex Keratopathy in a Patient Receiving Long-Term Ribociclib Therapy.
A 67-year-old woman with metastatic breast cancer was found on routine eye examination to have bilateral whorl-like corneal epithelial deposits after four years of continuous ribociclib therapy.
Abemaciclib and lenalidomide presenting with central retinal artery occlusion in a patient with breast cancer and multiple myeloma: a possible treatment-related association.
A woman in her late seventies with metastatic hormone receptor-positive breast cancer and multiple myeloma experienced sudden, painless vision loss in her right eye while on long-term abemaciclib and lenalidomide.
Buckle infection and exudative retinal detachment following a deep scleral bite: management and outcome.
During a standard 279 scleral buckle (SB) procedure, an inadvertent deep scleral suture bite occurred. On postoperative day (POD) 5, the patient presented with pain, reduced vision (counting fingers close to the face)…
Comparative study on the clinical effectiveness of low-concentration cyclosporine eye drops in patients with dry eye disease.
This multicenter, randomized, double-blind Phase 2 trial evaluated the efficacy and safety of low-concentration cyclosporine eye drops (SCAI-001 0.01% and 0.02%) versus Restasis (0.05%) in patients with dry eye disease.
Nine-year ocular developmental outcomes after ranibizumab or laser treatment for zone II retinopathy of prematurity: follow-up of a randomized trial cohort.
This study followed a randomized trial cohort to assess 9-year ocular developmental outcomes in children treated with intravitreal ranibizumab (IVR) or laser photocoagulation (LP) for zone II retinopathy of prematurity…
Non-Arteritic Anterior Ischaemic Optic Neuropathy Associated with Semaglutide use.
A woman in her 70s with vascular risk factors presented with a three-day history of progressive left-sided visual disturbance. Examination revealed a left relative afferent pupillary defect and inferior quadrantopia.
Functional Improvement with Red-Tinted Contact Lens in Pediatric Achromatopsia: A Case Report.
A child with achromatopsia presented with reduced visual acuity, photophobia, and impaired color discrimination. Following the fitting of red-tinted contact lenses, the patient reported significant improvements in glare…
Bacterial orbital infection leading to orbital exenteration: a case series.
This case series describes three people who underwent orbital exenteration for bacterial infection. Two infections arose from odontogenic sources; the third was periorbital/orbital necrotizing fasciitis associated with…
Clinical Reasoning: An Immunocompetent Young Adult With Acute Vision Loss.
A 23-year-old male presented with worsening headaches, bilateral retrobulbar pain, and blurred vision. Evaluation indicated bilateral optic neuritis, with MRI, CSF analysis, and blood tests showing normal results except…
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