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1034 articles
July 202624
Prognostic utility of tumor grade and IDH-mutation status for immunotherapy response in high grade glioma: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the prognostic value of tumor grade and IDH-mutation status in high-grade gliomas treated with immunotherapy.
Akkermansia muciniphila enhances washed microbiota transplantation in the treatment of epilepsy.
This prospective, single-center cohort study evaluated the efficacy and safety of washed microbiota transplantation (WMT) in 21 patients with epilepsy, primarily those with refractory cases.
Venous Sinus Stenting for Pulsatile Tinnitus: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the efficacy of venous sinus stenting (VSS) for treating pulsatile tinnitus (PT) in 850 patients, including those with idiopathic intracranial hypertension (IIH).
The Challenges of Compassion Bias in Clinical Decision-Making: A Case-Based Ethical Analysis.
A young woman with advanced neurologic decline due to HIV-associated progressive multifocal leukoencephalopathy had artificial enteral nutrition initially deferred by clinicians.
A systematic review of neuroimaging studies of adults aged 35 and older with clinical, symptomatic and genetic risk for attention-deficit/hyperactivity disorder.
This systematic review examined neuroimaging studies of adults aged 35 and older with clinical, symptomatic, or genetic risk for ADHD.
Intra-arterial thrombolytics after endovascular thrombectomy for acute ischemic stroke: A network meta-analysis of RCTs.
This network meta-analysis evaluated the efficacy and safety of intra-arterial thrombolysis (IAT) after endovascular thrombectomy (EVT) for acute ischemic stroke in 2564 patients across eight randomized controlled…
Novel splice-site and recurrent p.Arg729* CNKSR2 variants in ESES/CSWS: insights into sex-dependent expression.
This report describes two patients with de novo CNKSR2 variants. A 17-year-old female presented with a novel splice-site variant and a relatively mild phenotype, while an 8-year-old male exhibited a recurrent nonsense…
Strømme syndrome: the clinical and molecular spectrum associated with variants in CENPF.
Strømme syndrome (MIM 243605) or a form of syndromic microcephaly have both been reported to be caused by biallelic variants in CENPF.
Double-Negative Neuromyelitis Optica Spectrum Disorder: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined double-negative neuromyelitis optica spectrum disorder (DN-NMOSD) in 671 patients, comparing it to AQP4-NMOSD and MOGAD.
Minor stroke, major stakes: impact of procedure duration on thrombectomy outcomes in minor stroke.
This meta-analysis evaluated the impact of procedure duration on outcomes of endovascular thrombectomy (EVT) in 398 patients with minor stroke (NIHSS < 6) from the STAR registry.
Progressive Parkinsonism in PPP2R5D-Related Neurodevelopmental Disorder.
PPP2R5D-related neurodevelopmental disorder (Houge-Janssens syndrome type 1) is a rare autosomal dominant condition characterized by macrocephaly, intellectual disability, and epilepsy.
Effects of concurrent transcranial direct current stimulation on human motor skill learning: A systematic review and Bayesian meta-analysis.
This systematic review and Bayesian meta-analysis examined the effects of concurrent transcranial direct current stimulation (tDCS) on motor skill learning across 73 studies.
Phase III Open-Label, Randomized Clinical Trial of Epidermal Growth Factor and Growth Hormone Releasing Hexapeptide in Acute Ischemic Stroke.
The COURAGE-2 study was a multicenter, randomized, open-label phase III trial assessing the efficacy of intravenous Epidermal Growth Factor (75µg) and Growth Hormone Releasing Peptide-6 (5mg) in patients with acute…
Pesticide exposure and all health outcomes: An umbrella review of meta-analyses of observational studies.
This umbrella review systematically analyzed 53 meta-analyses of observational studies to evaluate the health outcomes associated with pesticide exposure.
Ischemic Postconditioning in Patients With Acute Stroke With Successful Recanalization After Endovascular Therapy: A Pilot Randomized Controlled Trial.
This pilot randomized controlled trial investigated the effect of ischemic postconditioning (IPostC) on infarct growth in 60 patients with acute ischemic stroke who achieved successful recanalization after endovascular…
Comparison of the Effects of Telerehabilitation-Based Motor and Cognitive Dual-Task Exercises in Patients With Parkinson's Disease-A Randomized Controlled Study.
This randomized controlled trial evaluated the effects of telerehabilitation-based motor-motor and cognitive-motor dual-task training in 30 patients with Parkinson's disease.
Coexisting Inflammatory and Hereditary Neuropathies: A Review.
This review presents two patients with both chronic inflammatory demyelinating polyneuropathy (CIDP) and Charcot-Marie-Tooth disease type 1A (CMT1A), alongside a review of reported overlap cases involving CMT1A, CMT1B…
Neuropsychiatric adverse events with anti-seizure medications in patients with epilepsy: A systematic review and meta-analysis.
This systematic review and meta-analysis synthesized observational evidence on neuropsychiatric adverse events (NPAEs) associated with anti-seizure medications (ASMs) in people with epilepsy.
Adherence to the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet and longitudinal changes in global cognition: a post hoc analysis of the MIND trial.
This post hoc analysis of the MIND trial evaluated the relationship between adherence to the MIND diet and changes in global cognition among 590 community-dwelling adults aged 65 to 84.
Effect of intravenous tirofiban on the radiologic classification of intracranial hemorrhage after endovascular treatment in acute anterior circulation occlusive stroke: results from the RESCUE BT trial.
This randomized controlled trial from the RESCUE BT study evaluated the impact of intravenous tirofiban on intracranial hemorrhage (ICH) subtypes in 945 patients undergoing endovascular treatment for acute anterior…
Brain abscess formation following cerebral infarction during treatment for hypervirulent Klebsiella pneumoniae meningoencephalitis: A case report.
A patient with rapidly progressive meningoencephalitis due to hypervirulent Klebsiella pneumoniae developed cerebral infarction and subsequent brain abscess formation during treatment.
Claudin-11-Mediated Hypomyelinating Leukodystrophy 22: New Insights Into Pathogenic Mechanisms.
A child presented with global developmental delay, hypotonia, limb hypertonia, esotropia, and absence of early milestones, later showing partial motor improvement but persistent cognitive impairment.
Magnolol as a promising multitarget agent for Alzheimer's disease: Evidence from a systematic evidence synthesis, network pharmacology, and molecular dynamics simulations.
This systematic review evaluated the therapeutic effects of magnolol (MN) in preclinical Alzheimer's disease models, integrating network pharmacology and molecular dynamics simulations.
Mineralizing Angiopathy as a Rare Etiology of Pediatric Stroke: Report of Three Cases.
Three infants aged 14 to 38 months presented with basal ganglia infarction following minor head trauma. Neuroimaging revealed lenticulostriate calcifications, confirming a diagnosis of mineralizing angiopathy.
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