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406 articles
October 20261
September 202623
Reducing Peripheral Intravenous Catheter Use in Adult Acute Care: A Systematic Review.
This systematic review evaluated interventions aimed at reducing peripheral intravenous catheter (PIVC) use in adult acute care settings.
Stroke mimic caused by severe hypomagnesemia: a case report and literature review.
A patient with a history of transient neurological deficits presented with stroke-like symptoms, including hemiparesis and aphasia. The patient was on Proton Pump Inhibitors and Metformin.
Reversible bilateral cerebellar ataxia resulting from hypercapnic encephalopathy in an undiagnosed patient with obstructive sleep apnoea.
A man in his 40s with morbid obesity and type 2 diabetes presented with early-morning drowsiness and respiratory distress after nocturnal dyspnoea and diuretic use.
Coexisting Postural Orthostatic Tachycardia Syndrome on Autonomic Reflex Testing in Functional Neurologic Disorder.
An 18-year-old woman with a prior diagnosis of functional neurological disorder (FND) presented with fluctuating lower-extremity weakness, gait disturbance, and recurrent drop attacks, alongside persistent orthostatic…
Non-thyroidal illness syndrome and isolated low triiodothyronine as prognostic markers in acute illness: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the relationship between thyroid hormone alterations and mortality in critically ill and cardiovascular patients.
Effects of concurrent training sequence on cardiometabolic risk factors in patients with type 2 diabetes: a systematic review and network meta-analysis.
This systematic review and network meta-analysis evaluated the effects of concurrent training sequences on cardiometabolic risk factors in patients with type 2 diabetes mellitus (T2DM).
Non-Arteritic Anterior Ischaemic Optic Neuropathy Associated with Semaglutide use.
A woman in her 70s with vascular risk factors presented with a three-day history of progressive left-sided visual disturbance. Examination revealed a left relative afferent pupillary defect and inferior quadrantopia.
A secondary analysis of the SODa-BIC randomized clinical trial using multiple hierarchical composite outcomes.
This post-hoc analysis of the SODa-BIC randomized trial evaluated the effects of sodium bicarbonate on Major Adverse Kidney Events at 30 days in critically ill patients with metabolic acidosis.
Early cardiovascular vulnerability after acute exacerbation of COPD: a time-windowed systematic review and evidence map.
This systematic review and evidence map examined cardiovascular events during and after exacerbations of COPD, asthma, or bronchiectasis, with COPD as the primary evidence base.
Within-person variability and the minimal important difference of the EQ-VAS in adults with post-COVID-19 condition: a secondary analysis of data from a single-centre randomised controlled trial.
This secondary analysis of a randomized controlled trial evaluated the EuroQol Visual Analogue Scale (EQ-VAS) in adults with post-COVID-19 condition (PCC).
Blood pressure targets for hypertension in people with diabetes mellitus.
This Cochrane systematic review protocol aims to evaluate whether lower blood pressure targets (≤ 130/85 mmHg) reduce mortality and morbidity compared to standard targets (≤ 140 to 160/90 to 100 mmHg) in individuals…
Multimorbidity and the risk of depression: a systematic review of cohort studies.
This systematic review evaluated the longitudinal association between multimorbidity and the risk of developing depression, analyzing 17 cohort studies.
The reduction in blood pressure required to reduce arterial stiffness components in SPRINT: a randomized controlled trial.
This analysis of the multicentre SPRINT randomised controlled trial examined whether blood pressure changes were associated with changes in arterial stiffness components over 1 year.
Opposite seasonal variation in nighttime and morning blood pressure: a longitudinal study of patients with hypertension.
This longitudinal study examined seasonal variations in nighttime and morning blood pressure (BP) among 419 hypertensive patients using home blood pressure monitoring.
Takayasu arteritis manifesting as pyrexia of unknown origin and massive splenomegaly.
A male patient in his early 20s presented with a three-month history of pyrexia of unknown origin, significant weight loss, a left carotid bruit, and massive splenomegaly.
Clinical Surveillance Technologies in Nonintensive Care Unit Hospital Settings: Systematic Review and Bayesian Network Meta-Analysis of Randomized Trials.
This systematic review and Bayesian network meta-analysis evaluated the clinical effects of rule-based electronic surveillance (RB-ES), predictive model-based electronic surveillance (PM-ES), and continuous physiologic…
Feasibility of an interdisciplinary primary care-based intervention to improve care transitions for hospitalized patients with substance use disorders: The IntACT pilot randomized controlled trial protocol.
The IntACT pilot study is a single-site randomized controlled trial assessing the feasibility and preliminary effectiveness of a primary care-based intervention for hospitalized patients with substance use disorders…
Approved Medications for Substance Use Disorders: An Umbrella Review of Systematic Reviews and Completed Phase 3 Randomized Controlled Trials.
This PROSPERO-registered umbrella review synthesised systematic reviews and completed phase 3 randomised trials of approved and pipeline medications for substance use disorders worldwide.
Housing Instability Associated With Cost-Related Nonadherence and Financial Toxicity in People With Uncontrolled Diabetes.
This randomized controlled trial examined the prevalence of housing instability among 600 adults with uncontrolled diabetes and its impact on cost-related nonadherence and financial toxicity.
Direct oral anticoagulants vs warfarin in Asian vs non-Asian patients with atrial fibrillation: a patient-level meta-analysis from COMBINE AF.
This patient-level meta-analysis compared clinical outcomes of direct oral anticoagulants (DOACs) versus warfarin in 10,212 Asian and 61,471 non-Asian patients with atrial fibrillation.
Semi-recumbent position for the prevention of ventilator-associated pneumonia in adults requiring mechanical ventilation.
This systematic review and meta-analysis evaluated the effectiveness of semi-recumbent positioning for preventing ventilator-associated pneumonia (VAP) in mechanically ventilated ICU patients.
Implementation of a patient-centred complex intervention to improve Initial Medication Adherence to cardiovascular disease and diabetes treatments in primary care (the IMA-cRCT study): a mixed-methods process evaluation.
The IMA-cRCT study evaluated a patient-centred intervention aimed at improving initial medication adherence for cardiovascular disease and diabetes in primary care across 24 Spanish centres.
Barriers and enablers to deprescribing from the perspectives of older adults with polypharmacy and their stakeholders: A systematic review of qualitative studies.
This systematic review synthesised qualitative studies on barriers and enablers to deprescribing among older adults with polypharmacy and relevant stakeholders.
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