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1088 articles
December 202512
Interventions targeting executive functions in children and young people exposed to complex trauma: A systematic review.
This PRISMA-guided systematic review examined interventions targeting executive function (EF) in children and young people exposed to complex trauma, including abuse, neglect, and violence.
Efficacy of Brexpiprazole on Neuropsychiatric Symptoms and Impact on Caregivers: Pooled Neuropsychiatric Inventory (NPI) Analysis in Patients With Agitation Associated With Dementia due to Alzheimer's Disease.
This exploratory pooled analysis examined Neuropsychiatric Inventory (NPI) outcomes from two randomized, double-blind, placebo-controlled trials of brexpiprazole for agitation associated with Alzheimer’s disease…
Improving Community-Based Care for Adolescents with ADHD: a Randomized Controlled Trial of Artificial Intelligence-Assisted Fidelity Supports.
This randomized controlled trial evaluated whether AI-assisted implementation supports improved delivery of Supporting Teens’ Autonomy Daily (STAND), a cognitive-behavioral treatment blended with Motivational…
Stratified Stepped-Care for Reducing Suicide Attempts and Self-Harm in Youth: A Randomized Clinical Trial.
This randomized clinical trial evaluated whether adding stratified stepped-care for suicide prevention (SC-SP) to Zero Suicide quality improvement (ZSQI) reduced suicidal behavior among 301 youth aged 12–24 selected for…
Weapon or Armor? Unpacking the Paradox of Narcissism and Self-Reported Mental Health Through a Three-Level Meta-Analysis.
This three-level meta-analysis examined associations between dimensions of narcissism and mental health, particularly internalizing psychopathology.
A systematic review and meta-analysis of routine white blood cell concentrations in people with eating disorders.
This systematic review and meta-analysis examined white blood cell (WBC) concentrations and subtypes in people with anorexia nervosa (AN) or bulimia nervosa (BN), compared with healthy controls, and during weight…
Treatment outcomes of sexual minority women (SMW) veterans with military sexual trauma (MST).
This secondary analysis of a randomized clinical trial examined treatment outcomes among women veterans with military sexual trauma and posttraumatic stress disorder, comparing skills training in affective and…
The association between treatment integrity and treatment outcome of cognitive behavioural therapy for major depressive disorder.
This study examined whether treatment integrity—therapist adherence to and competence in cognitive behavioural therapy (CBT)—was associated with outcomes for major depressive disorder (MDD).
Efficacy and Safety of Auricular Acupressure for Insomnia in Patients With Functional Dyspepsia: A Randomized Controlled Trial.
This randomized controlled trial evaluated auricular acupressure (AA) for insomnia in patients with functional dyspepsia (FD), comparing treatment at the ear concha with sham acupressure at the earlobe.
Can depression and anxiety apps improve quality of life, wellbeing, and disability outcomes? Meta-analysis of randomized controlled trials.
This meta-analysis of 25 randomized controlled trials assessed whether mental health apps for depression and anxiety improve quality of life, general wellbeing, and disability. Most trials focused on depression.
Breakthroughs in emotional awareness: Exploring sudden gains in internet-based psychodynamic therapy for depressed adolescents.
This qualitative analysis explored processes surrounding sudden gains (SGs) during internet-delivered psychodynamic therapy (IPDT) for adolescent depression.
Domain-Specific Efficacy of Accelerated Repetitive Transcranial Magnetic Stimulation in Neuropsychiatric Disorders: A Systematic Review and Meta-Analysis.
This preregistered systematic review and random-effects meta-analysis assessed accelerated repetitive transcranial magnetic stimulation (arTMS; at least two sessions daily) versus sham in randomized trials across…
November 20258
Exploring early add-on celecoxib treatment in OCD: Results from a preliminary randomized, double-blind, placebo-controlled trial.
This preliminary randomized, double-blind, placebo-controlled trial evaluated celecoxib added early to fluoxetine in 44 drug-naive patients with obsessive-compulsive disorder over 8 weeks.
Efficacy and Methodology of Remote Heart Rate Variability Biofeedback Interventions for Mental Health: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed remote heart rate variability biofeedback (HRV-B) for mental health symptoms and HRV across 18 studies involving 1,352 participants from different populations.
Oral Methods of Microbiota Manipulation for Depression Symptoms: A Systematic Review: Méthodes orales de manipulation du microbiote pour traiter les symptômes de dépression : Une revue systématique.
This systematic review examined completed parallel-arm randomised controlled trials of oral microbiota manipulation and depressive symptoms in adults not taking antidepressants.
Implementation of a Face-To-Face Vs Virtual Peer-Integrated Collaborative Care Intervention for Mental Health Treatment of Physical Trauma Survivors: A Qualitative Study of Lessons from the COVID-19 Pandemic.
This qualitative study examined how the COVID-19 pandemic affected implementation of a peer-integrated collaborative care intervention for mental health among 450 patients receiving treatment for physical injuries.
Examining the relationship between pre-treatment anhedonia and treatment outcomes in individuals with anxiety or depression: A systematic review.
This systematic review examined whether pre-treatment anhedonia or lower reward sensitivity was associated with outcomes of psychotherapy, pharmacotherapy, or neuromodulation in people with anxiety or unipolar…
Review: Adolescents' perspectives on and experiences with post-primary school-based suicide prevention as end-users, co-creators and peer helpers - a systematic review meta-ethnography.
This systematic review and meta-ethnography synthesised qualitative research on adolescents’ experiences of post-primary school-based suicide prevention interventions.
The effectiveness of supplemental and replacement blended cognitive behavioral therapy for internalizing disorders: a meta-analysis.
This meta-analysis examined blended cognitive behavioral therapy (bCBT), which combines face-to-face and online therapy, for internalizing disorders including anxiety and depression.
AboutFace: A randomized controlled evaluation of an online peer-based intervention to increase PTSD treatment engagement.
This randomized controlled trial evaluated AboutFace, an online peer-based intervention, against a psychoeducational brochure in 330 veterans referred for PTSD treatment after a specialty-clinic intake.
October 20254
Implementation of an integrated community-based suicide prevention programme, Gujarat, India: cluster randomised controlled trial.
This pragmatic cluster randomised controlled trial tested an integrated suicide prevention programme in villages in Mehsana, India.
Effectiveness of a Nurse Practitioner-Led Collaborative Healthcare Model in Reducing Anxiety and Depression and Improving Quality of Life in Patients With Heart Failure: A Randomized Controlled Trial.
This randomized controlled trial evaluated a nurse practitioner-led collaborative healthcare model for anxiety, depression, and quality of life among 100 patients with heart failure at a regional teaching hospital in…
Treatment for co-occurring posttraumatic stress disorder and substance use disorders among veterans and civilians: A test of causally moderated comparative effectiveness.
This meta-analysis used secondary analyses of psychotherapy-arm data from 26 randomised controlled trials involving 3,228 veterans and civilians with co-occurring posttraumatic stress disorder (PTSD) and substance use…
Understanding Alliance Discrepancies in Youth Therapy: A Case Study of Rupture and Repair in CBT.
A case study examined cognitive behavioral therapy for an adolescent with depression, using session recordings, alliance ratings, and post-therapy interviews with the adolescent and therapist.
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