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1034 articles

September 20256

Clinical ResearchNeurology

N-acetylcysteine for Parkinson's disease: a translational systematic review of mechanistic and early clinical data.

This PRISMA-compliant systematic review assessed preclinical and prospective clinical evidence on N-acetylcysteine (NAC) for Parkinson’s disease, including motor outcomes, dopaminergic imaging, glutathione and safety.

Neurodegener Dis ManagSep 24, 2025Read summary
Clinical ResearchNeurologyOpen access

Distal versus proximal guide catheter placement on the safety and efficacy of mechanical thrombectomy for acute ischemic stroke in anterior circulation: A systematic review and meta-analysis.

This systematic review and meta-analysis pooled seven retrospective comparative studies of 2,148 adults undergoing mechanical thrombectomy for anterior-circulation large-vessel-occlusion stroke.

Interv NeuroradiolSep 24, 2025Read summary
Clinical ResearchNeurologyOpen access

An evidence-based pulsatile tinnitus clinical workflow: A systematic review of literature.

This systematic review examined recent literature on pulsatile tinnitus (PT) diagnosis and management to develop referral criteria for neuroendovascular teams.

Interv NeuroradiolSep 24, 2025Read summary
Clinical ResearchNeurologyOpen access

The Synergistic Effects of Trunk Rehabilitation Exercise and Transcranial Direct Current Stimulation on Brain-derived Neurotrophic Factor Levels in Stroke Recovery.

This randomized controlled trial evaluated trunk rehabilitation exercise (TRE), transcranial direct current stimulation (tDCS), and their combination in 69 stroke survivors, measuring serum brain-derived neurotrophic…

Ann Afr MedSep 16, 2025Read summary
Case ReportNeurologyOpen access

An Emerging Autoimmune Neuroinflammatory Disease: Myelin Oligodendrocyte Glycoprotein Antibody Disease.

A 40-year-old woman presented with fever, acute left visual impairment and pain with eye movement, ataxia, dizziness, bitemporal headache, and urinary retention.

Ann Afr MedSep 15, 2025Read case
Clinical ResearchNeurology

Endovascular thrombectomy versus medical management for basilar artery occlusion stroke with mild neurological deficit - results from the BASILAR registry.

This comparative analysis examined endovascular thrombectomy (EVT) plus medical management versus medical management alone in acute basilar artery occlusion with mild neurological deficits (NIHSS ≤10).

Neurol ResSep 13, 2025Read summary

August 20255

Clinical ResearchNeurologyOpen access

Associations of cognitive intraindividual variability with Alzheimer's disease risk: A systematic review.

This systematic review synthesised 44 studies of cognitive intraindividual variability (IIV)—inconsistency or dispersion across cognitive measures—in relation to Alzheimer’s disease (AD) risk.

Clin NeuropsycholAug 22, 2025Read summary
Case ReportMedical GeneticsOpen access

Ataxia and oculomotor apraxia caused by a large-scale deletion in the senataxin gene.

Two adult patients developed cerebellar syndrome, scanned speech and exercise intolerance beginning in the second or third decade, followed by muscle weakness and impaired gait coordination.

J Appl GenetAug 20, 2025Read case
Clinical ResearchGeriatricsOpen access

The Effect of the Care Ecosystem Collaborative Care Model on End-of-Life Outcomes for People With Dementia and Their Caregivers.

This mixed-methods analysis of a randomized controlled trial evaluated the telephone-based Care Ecosystem collaborative care model in people with dementia and their caregivers, focusing on end-of-life outcomes.

Am J Hosp Palliat CareAug 19, 2025Read summary
Case ReportNeurology

Unusual Urgent Case Presenting to the EDX Lab: Mononeuropathy Monoplex.

A previously healthy 30-year-old woman developed sudden left leg pain, tingling, and sensory loss after hospitalization for presumed urosepsis.

Am J Phys Med RehabilAug 13, 2025Read case
Clinical ResearchNeurologyOpen access

Intra-arterial thrombolysis after successful endovascular reperfusion for large vessel occlusion stroke: A meta-analysis of randomized seven controlled trials.

This systematic review and meta-analysis compared intra-arterial thrombolysis (IAT) with placebo after successful endovascular recanalization for acute ischemic stroke due to large-vessel occlusion.

Interv NeuroradiolAug 13, 2025Read summary

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