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1316 articles

October 202624

Clinical ResearchGeriatricsOpen access

Thermographic outcomes of auricular laser acupuncture and auricular seed acupressure in older adults with chronic shoulder pain: an exploratory nonrandomized, nonconcurrent comparison.

This exploratory, open-label, nonrandomized comparison studied 20 adults aged 60–90 years with chronic shoulder pain, allocated by order of entry to auricular laser acupuncture or seed acupressure.

Lasers Med SciOct 21, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Feasibility and safety of an exercise-based prehabilitation intervention before cancer surgery: a pilot randomised controlled trial.

This single-centre pilot randomised controlled trial assessed the feasibility and safety of supervised aerobic prehabilitation before surgery in patients with breast, colorectal, or prostate cancer.

Support Care CancerOct 21, 2026Read summary
Clinical ResearchOphthalmology

ULTRAWIDE-FIELD COLOR FUNDUS IMAGES AND ARTIFICIAL INTELLIGENCE FOR DIAGNOSIS OF DIABETIC RETINOPATHY: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed artificial intelligence (AI) for diabetic retinopathy (DR) evaluation using ultrawide-field fundus images.

RetinaOct 21, 2026Read summary
Clinical ResearchOncology (Medical)

The prognostic value of physical functioning on survival in patients with nonsmall cell lung cancer: a systematic review and meta-analysis.

This systematic review and meta-analysis examined whether objectively measured physical functioning predicts survival in adults with nonsmall cell lung cancer (NSCLC), across surgical and nonsurgical treatment groups.

Eur Respir RevOct 21, 2026Read summary
Clinical ResearchGeriatricsOpen access

Feasibility of a multidimensional interdisciplinary rehabilitation program for people with dementia and their informal primary caregivers - a randomized pilot trial with a caregiver focus.

This randomized pilot trial assessed the feasibility of a person-centred, interdisciplinary rehabilitation program for community-dwelling people with dementia that also provided education and support to informal…

BMC GeriatrOct 21, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

Systematic review and meta-analysis of mesh versus suture repairs of small umbilical hernias (≤ 2 cm).

This systematic review and meta-analysis compared mesh with suture repair for small umbilical hernias (defects ≤ 2 cm). The primary outcome was postoperative recurrence; secondary outcomes included complications and…

HerniaOct 21, 2026Read summary
Clinical ResearchOrthopedic Surgery

Additional Functional Exercise Training Improves Knee Recovery After Meniscus Repair: A Randomized Controlled Trial.

This prospective randomized controlled trial assessed whether functional exercise training (FET) added to conventional rehabilitation improves recovery after meniscus repair.

J Vis ExpOct 21, 2026Read summary
Clinical ResearchPediatrics

Ruxolitinib for the treatment of pediatric acute and chronic steroid-refractory graft-versus-host disease: Efficacy, safety, and outcomes.

This single-center retrospective study assessed ruxolitinib in children under 18 years with steroid-refractory graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.

Hematol Oncol Stem Cell TherOct 21, 2026Read summary
Clinical ResearchGastroenterology

Acetic acid chromoendoscopy for detection of neoplastic Barrett's oesophagus: stepped wedge cluster randomised controlled trial (ACID-trial).

This prospective, open-label, stepped-wedge cluster randomised trial assessed whether acetic acid chromoendoscopy (AAC) improved detection of dysplasia or oesophageal adenocarcinoma during Barrett’s oesophagus…

BMJOct 21, 2026Read summary
Clinical ResearchEndocrinology

The Effect of Obesity on the α-Cell Response to Hyperglycemia in the Presence of Amino Acids.

This randomized, two-occasion study examined how amino acids affect glucagon suppression during graded glucose infusion in lean participants and participants with obesity, with or without hepatic steatosis.

DiabetesOct 21, 2026Read summary
Clinical ResearchOphthalmology

EVALUATING THE EFFICACY AND SAFETY OF TOPICAL DIFLUPREDNATE IN PATIENTS WITH CHRONIC CENTRAL SEROUS CHORIORETINOPATHY.

This pilot, open-label randomized controlled trial compared topical difluprednate, oral eplerenone, and observation in adults with chronic or relapsing central serous chorioretinopathy.

RetinaOct 21, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

The effects of perinatal depression and anxiety on memory, attention, and cognitive flexibility: a systematic review and meta-analysis.

This systematic review and meta-analysis examined whether perinatal depressive and anxiety symptoms are associated with memory, attention, and cognitive flexibility.

Arch Womens Ment HealthOct 21, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Outcomes of Mindful Mood Balance for Moms, online mindfulness-based cognitive therapy for perinatal depressive relapse prevention in the USA: a two-arm, single-blind, pragmatic randomised clinical trial.

This single-blind, pragmatic randomised clinical trial tested a web-based mindfulness-based cognitive therapy programme plus usual care against usual care alone in euthymic pregnant women with recurrent depression and…

Lancet Public HealthOct 21, 2026Read summary
Clinical ResearchPediatricsOpen access

Parent-child discrepancies in health-related quality of life in pediatric celiac disease: a systematic review and meta-analysis.

This systematic review and meta-analysis examined child–parent differences in health-related quality of life (HRQoL) among children and adolescents with celiac disease, using the disease-specific CDDUX questionnaire.

Eur J PediatrOct 21, 2026Read summary
Clinical ResearchEmergency Medicine

A multifaceted intervention to increase bystander CPR rates after out-of-hospital cardiac arrest in France: a stepped-wedge, cluster-randomised, controlled trial.

This stepped-wedge, cluster-randomised controlled trial assessed a coordinated intervention to increase bystander CPR before EMS arrival among adults with non-traumatic out-of-hospital cardiac arrest in France.

Lancet Public HealthOct 21, 2026Read summary
Clinical ResearchGastroenterology

Effects of Aerobic Exercise on Autonomic and Endothelial Function and Splanchnic Hemodynamics in Compensated Cirrhosis: RCT Study.

This parallel-group randomised controlled trial assessed 16 weeks of moderate-intensity aerobic exercise plus nutritional consultation versus nutritional consultation alone in 50 sedentary patients with compensated…

Liver IntOct 21, 2026Read summary
Clinical ResearchPulmonology

Interventions to increase participation in lung cancer screening programmes: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed interventions to improve informed choice and participation in low-dose CT lung cancer screening.

Eur Respir RevOct 21, 2026Read summary
Clinical ResearchHematology

The role of allogeneic hematopoietic stem cell transplantation in adults with mature T-cell lymphomas.

This Cochrane systematic review and meta-analysis assessed allogeneic stem cell transplantation (alloSCT) for adults with mature T-cell lymphomas (MTCL), as first-line or salvage treatment.

Cochrane Database Syst RevOct 21, 2026Read summary
Clinical ResearchEndocrinology

Excess Liver Fat in Type 2 Diabetes Stratified by Intrapancreatic Fat Deposition: A Meta-Analysis of Dual-Organ MRI Studies.

This meta-analysis pooled dual-organ MRI studies comparing liver fat content (LFC) in people with type 2 diabetes (T2DM) and non-diabetic controls, and examined whether study-level intrapancreatic fat deposition (IPFD)…

Liver IntOct 21, 2026Read summary
Clinical ResearchCardiologyOpen access

Effectiveness and safety of atorvastatin/ ezetimibe fixed-dose combination in hypercholesterolemia: a systematic review and network meta-analysis.

This systematic review and network meta-analysis compared atorvastatin alone with atorvastatin/ezetimibe free-equivalent and fixed-dose combinations in people with hypercholesterolemia.

PeerJOct 21, 2026Read summary
Clinical ResearchPsychiatry

"The Effect of Forgiveness Psychoeducation on Death Anxiety, Caregiver Burden, and Forgiveness Tendencies in Caregivers of Patients at the End of Life: A Randomized Controlled Trial": Şahin 49(3) May/June 2026.

This randomized controlled trial evaluated forgiveness psychoeducation for 56 caregivers of patients at the end of life, with 28 assigned to the intervention and 28 to a no-intervention control group.

Cancer NursOct 21, 2026Read summary
Clinical ResearchEndocrinology

Baseline Serum Metabolites as Predictors of Teplizumab Response in Individuals With Type 1 Diabetes.

This analysis examined whether baseline serum metabolites could predict response to teplizumab in 41 people newly diagnosed with type 1 diabetes who participated in the randomized AbATE trial.

DiabetesOct 21, 2026Read summary
Clinical ResearchRheumatologyOpen access

Association between rheumatic diseases and glaucoma risk: a systematic review and meta-analysis of 5.7 million individuals.

This systematic review and meta-analysis examined glaucoma occurrence and risk among people with rheumatic diseases (RD), drawing on 18 studies with 5,766,143 participants.

Int OphthalmolOct 21, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Sevuparin in children with severe malaria: a phase I safety and dose-finding trial.

This phase I dose-finding trial assessed sevuparin safety and tolerability in Kenyan and Zambian children with severe malaria.

Nat CommunOct 21, 2026Read summary

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