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1891 articles
February 20266
Perioperative Management of Targeted and Immunologic Agents in Neurosurgical Oncology.
This systematic review examined perioperative risks and management of targeted and biologic cancer therapies in patients undergoing neurosurgical procedures, drawing on clinical trials, safety data, meta-analyses, and…
Therapeutic Impact of Third-generation Tyrosine Kinase Inhibitors on Lung Squamous Cell Carcinoma with Epidermal Growth Factor Receptor Mutations: A Case Description and Systematic Literature Review.
The abstract describes a case of lung squamous cell carcinoma (SQC) with an EGFR mutation, alongside a systematic review of 34 eligible cases.
Successful Treatment of Synchronous Double Lung and Colon Cancers Using Immune Checkpoint Inhibitors.
A patient presented with synchronous advanced cancers: PD-L1-negative squamous cell carcinoma in the left upper lung lobe and adenocarcinoma of the ascending colon.
Warm Autoimmune Hemolytic Anemia Associated with Pancreatic Adenocarcinoma Showing Ectopic Expression of Band 3 Protein: A Case Report.
A 73-year-old woman with unresectable pancreatic adenocarcinoma developed warm autoimmune hemolytic anemia that was refractory to steroids. Prednisolone partially improved the anemia but did not control hemolysis.
Status Epilepticus as the Initial Manifestation of Follicular Lymphoma with Leptomeningeal Dissemination.
A 44-year-old man presented with meningoencephalitis and developed status epilepticus. Evaluation showed diffuse leptomeningeal dissemination of grade 1 follicular lymphoma, despite negative cerebrospinal fluid cytology.
Acute Lower Limb Arterial Occlusion Due to Malignant Lymphoma.
A 72-year-old man presented with acute pain and weakness in the left lower limb and was diagnosed with arterial occlusion. Examination of the thrombectomy specimen identified fibrin-associated diffuse large B-cell…
January 202618
Unusual Presentation of Dual Left Atrial Masses Including Pulmonary Vein Involvement: A Rare Spindle Cell Sarcoma.
An 82-year-old woman presented with dizziness, and evaluation identified two left atrial masses, including pulmonary vein involvement. The masses were resected with clear margins; no metastases were initially found.
GvHD and GRFS in patients with acute myeloid leukemia undergoing allogeneic HCT with treosulfan- versus reduced-intensity busulfan-based conditioning: a subgroup analysis of a randomized phase 3 trial.
This subgroup analysis of a randomized phase III trial compared treosulfan-fludarabine with reduced-intensity busulfan-fludarabine conditioning in 352 patients aged 31–70 years with acute myeloid leukemia undergoing…
Efficacy of pegfilgrastim in preventing febrile neutropenia during DCF chemotherapy for esophageal cancer: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed prophylactic pegfilgrastim for preventing febrile neutropenia (FN) in patients with esophageal cancer receiving docetaxel, cisplatin, and fluorouracil (DCF)…
Baseline D-dimer as a predictor of immune checkpoint inhibitor efficacy in cancer.
This systematic review and meta-analysis examined whether baseline D-dimer predicts outcomes in cancer patients receiving immune checkpoint inhibitors.
Progressive multifocal leukoencephalopathy associated with elranatamab therapy in relapsed/refractory multiple myeloma.
A 67-year-old woman with relapsed/refractory multiple myeloma achieved a complete response with elranatamab, a BCMA- and CD3-targeting bispecific antibody.
Efficacy and Safety of Camrelizumab Combination Therapy in Triple-Negative Breast Cancer: A Systematic Review and Meta-Analysis.
This systematic review and random-effects meta-analysis assessed efficacy and safety of camrelizumab combination therapy in women with triple-negative breast cancer. Nine studies involving 357 patients were pooled.
Risk of bone fractures in patients with prostate cancer treated with maximal androgen blockade therapy: a systematic literature review and meta-analysis.
This systematic review and meta-analysis examined fracture risk with maximal androgen blockade (MAB)—androgen deprivation therapy (ADT) plus an androgen receptor pathway inhibitor—versus ADT alone in patients with…
Human Epidermal Growth Factor Receptor-2 positive metastatic salivary duct carcinoma with remarkable response to targeted therapy: a case report and therapeutic implications.
A middle-aged man with metastatic salivary duct carcinoma (SDC) had a HER2-positive tumour. Treatment with trastuzumab and docetaxel was followed by a near-complete pathological and radiological response, which enabled…
Elevated C-reactive protein to albumin ratio is a promising predictive biomarker for prognosis in patients with renal cell carcinoma.
This meta-analysis assessed whether baseline C-reactive protein to albumin ratio (CAR) predicts prognosis in patients with renal cell carcinoma (RCC). It included 10 studies comprising 2478 patients.
Eating Experiences During Cancer Treatment in Adolescents and Young Adults: A Systematic Literature Review and Meta-Synthesis.
This systematic literature review and qualitative meta-synthesis examined eating experiences and mealtime-related well-being among adolescents and young adults aged 15–39 receiving cancer treatment.
Acquired FGFR2 mutation leads resistance to pemigatinib in a patient with FGFR2-driven Borrmann type IV gastric cancer.
A 47-year-old woman with advanced, chemotherapy-refractory Borrmann type IV gastric cancer had FGFR2 rearrangement and amplification.
Inferior Vena Cava Resection Using Modified Veno-Venous Bypass With Renal Vein Drainage: Case Report Adapted From Liver Transplant Practice.
A patient with recurrent renal cell carcinoma invading the inferior vena cava (IVC) and left renal vein confluence had a solitary kidney after right nephrectomy.
Endobronchial ultrasound-guided mediastinal biopsies for the diagnosis of mediastinal diseases: A network meta-analysis.
This network meta-analysis assessed the efficacy and safety of EBUS-guided biopsy strategies for mediastinal diseases, drawing on 15 prospective studies with 1,316 participants.
Prolonged progression-free survival with zanubrutinib in relapsed/refractory CLL: an indirect treatment comparison versus other BTK inhibitors using multilevel network meta-regression.
This multilevel network meta-regression compared zanubrutinib with acalabrutinib and ibrutinib for relapsed/refractory chronic lymphocytic leukemia, estimating effects in general and high-risk populations.
Epithelioid Trophoblastic Tumor Presenting as a Large Cystic Mass: Diagnostic Clue From Foreign DNA Sequences Detected by Comprehensive Genomic Profiling.
A postmenopausal woman in her 50s presented 20 years after her last pregnancy with a 19-cm multilocular cystic mass protruding from the cervix, initially suspected to be infected.
Efficacy and safety of adjuvant capecitabine and pembrolizumab in early-stage triple-negative breast cancer after standard neo-/adjuvant chemotherapy: A meta-analysis of phase III studies.
This systematic review and meta-analysis pooled four phase III randomised trials involving 3133 participants with early-stage triple-negative breast cancer, comparing outcomes with adjuvant capecitabine or pembrolizumab…
Children's outcomes in medulloblastoma proton versus photon craniospinal radiotherapy (CURE): meta-analysis.
This systematic review and meta-analysis compared proton with photon craniospinal irradiation (CSI) in children younger than 21 years with medulloblastoma.
Efficacy and safety of adjuvant chemotherapy for locally advanced cervical carcinoma: an updated Systematic review and meta-analysis.
This systematic review and meta-analysis compared adjuvant chemotherapy (ACT) after concurrent chemoradiotherapy (CCRT) with CCRT alone for locally advanced cervical cancer.
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