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Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

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FeaturedClinical ResearchGeneral Surgery

Impact of PerioperAtive LidocAine Infusions on Enhanced Recovery After Noncardiac Surgery (IMPALA-ERAS) in an inpatient setting: rationale, design and protocol for a sequential, repeated crossover trial.

BMJ OpenSep 8, 2026

The IMPALA-ERAS trial is a single-centre, pragmatic, cluster-randomised, double-blinded, placebo-controlled study evaluating the effects of perioperative intravenous lidocaine infusions on postoperative recovery in 2290…

Why it matters

Understanding the role of intravenous lidocaine in ERAS pathways could enhance postoperative recovery and reduce opioid consumption, addressing the ongoing challenge of opioid-related complications in surgical patients.

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Also worth knowing

Clinical ResearchGeneral Surgery

Minimally invasive versus open abdominoperineal resection and the risk of postoperative perineal hernia: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the risk of postoperative perineal hernia in 763 patients undergoing minimally invasive versus open abdominoperineal resection (APR) or extralevator abdominoperineal…

HerniaSep 9, 2026Open accessRead summary
Clinical ResearchGeneral Surgery

Comparison of laparoscopic intraperitoneal onlay mesh (IPOM Plus) and extended totally extraperitoneal (eTEP RS) repair for incisional hernia - a randomized clinical trial.

This randomized clinical trial compared laparoscopic intraperitoneal onlay mesh (IPOM Plus) and extended totally extraperitoneal (eTEP RS) repair techniques in 72 patients with midline incisional ventral hernias.

HerniaSep 4, 2026Open accessRead summary
Clinical ResearchGeneral Surgery

Efficacy and safety of laparoscopic-guided transversus abdominis plane block versus port-site local anesthetic infiltration in laparoscopic cholecystectomy: A systematic review, meta-analysis, and trial sequential analysis.

This systematic review and meta-analysis evaluated the efficacy and safety of laparoscopic-guided transversus abdominis plane (LTAP) block versus port-site local anesthetic infiltration in 711 patients undergoing…

Medicine (Baltimore)Sep 4, 2026Read summary
Clinical ResearchOncology (Medical)

Use of indocyanine green fluorescence versus patent blue V dye for sentinel lymph node biopsy in early breast cancer, a randomized controlled trial.

This randomized controlled trial compared indocyanine green (ICG) fluorescence with patent blue V (PBV) dye for sentinel lymph node biopsy in 40 patients with early-stage, node-negative breast cancer.

J Egypt Natl Canc InstSep 2, 2026Open accessRead summary
Clinical ResearchAnesthesiology

Analgesic Effects of Intravenous Lidocaine in Laparoscopic Surgery: A Systematic Review and Meta-Analysis With Trial Sequential Analysis.

This systematic review and meta-analysis evaluated the effects of intravenous lidocaine on postoperative pain in adults undergoing laparoscopic surgery, including 45 randomized clinical trials with 2599 patients.

Clin J PainSep 1, 2026Read summary
Clinical ResearchGeneral Surgery

Incidence and predictors of surgical recurrence after primary ileocolic resection in Crohn ileitis: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the incidence and predictors of surgical recurrence after primary ileocolic resection (ICR) in patients with Crohn disease.

Inflamm Bowel DisSep 1, 2026Open accessRead summary
Clinical ResearchAnesthesiology

Etomidate combined with TAPB in ovarian cancer surgery: A controlled study on hemodynamics and immune response.

This randomized controlled trial evaluated the effects of etomidate combined with transversus abdominis plane block (TAPB) on hemodynamics and immune response in 80 patients undergoing ovarian cancer surgery.

Pak J Pharm SciSep 1, 2026Read summary
Clinical ResearchAnesthesiology

Rebound Pain and Patient Satisfaction With Dexamethasone as an Adjunct for Peripheral Nerve Blocks. A Substudy Based on Two Randomised Clinical Trials.

This substudy pooled data from two randomized controlled trials to evaluate the effect of dexamethasone on pain and rebound pain after peripheral nerve blocks in 159 patients undergoing osseous surgery.

Acta Anaesthesiol ScandSep 1, 2026Open accessRead summary
Clinical ResearchOncology (Medical)

KangDuo surgical robot KD-SR-01 versus da Vinci Xi in robot-assisted colorectal cancer resection: oncologic outcomes at three years in a multicenter randomized trial.

This multicenter randomized trial compared the long-term oncologic outcomes of the KangDuo surgical robot KD-SR-01 and the da Vinci Xi in 100 patients undergoing colorectal cancer resection.

J Robot SurgSep 1, 2026Open accessRead summary
Clinical ResearchGeneral Surgery

Thoracoscopic internal fixation, open surgical internal fixation, and conservative treatment of rib fractures: differences in postoperative rehabilitation and chest volume (a randomized controlled trial).

This randomized controlled trial evaluated the efficacy of thoracoscopic internal fixation, open surgical internal fixation, and conservative treatment for multiple rib fractures in patients at Weifang People's…

Eur J Trauma Emerg SurgAug 31, 2026Open accessRead summary
Clinical ResearchNeurology

The Neurological Impact of Metabolic and Bariatric Surgery: A Systematic Review of Post-Operative Neuropathic and Non-Neuropathic Complications.

This systematic review evaluated neurological complications following metabolic and bariatric surgery in over 5000 patients.

Clin ObesSep 6, 2026Open accessRead summary

Showing 12 of 25 publications that cleared our clinical screen in the last 14 days.

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