Trending Now

Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

AllClinical ResearchCase Reports
FeaturedClinical ResearchGeneral Surgery

Prophylactic neurectomy versus nerve preservation in open inguinal hernia repair for prevention of chronic postoperative inguinal pain (CPIP): a systematic review and meta-analysis.

HerniaOct 23, 2026Open access

This systematic review and meta-analysis assessed prophylactic neurectomy versus nerve preservation in adults undergoing elective open anterior inguinal hernia repair, including 17 randomized trials.

Why it matters

Chronic pain is an important source of disability after open inguinal hernia repair, and the pooled results suggest prophylactic neurectomy may reduce its occurrence.

Read summary

Also worth knowing

Clinical ResearchGeneral SurgeryOpen access

Systematic review and meta-analysis of mesh versus suture repairs of small umbilical hernias (≤ 2 cm).

This systematic review and meta-analysis compared mesh with suture repair for small umbilical hernias (defects ≤ 2 cm). The primary outcome was postoperative recurrence; secondary outcomes included complications and…

HerniaOct 21, 2026Read summary
Clinical ResearchCardiologyOpen access

Cold and Room-Temperature Platelets in Cardiac Surgery: The CHIPS Randomized Clinical Trial.

The phase 3, multicenter, randomized CHIPS trial compared cold-stored platelets (CSPs; up to 21 days) with room-temperature platelets (RTPs; up to 7 days) in pediatric and adult patients receiving platelet transfusions…

JAMAOct 13, 2026Read summary
Clinical ResearchPediatricsOpen access

Neonatal gastric perforation: a systematic review and meta-analysis of clinical characteristics, risk factors, surgical management and outcomes.

This systematic review and meta-analysis examined clinical features, risk factors, surgical management and outcomes of neonatal gastric perforation using observational studies of neonates aged 28 days or younger.

Pediatr Surg IntOct 20, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Neoadjuvant Therapy for Gastric Adenocarcinoma with Signet Ring Cells: A Systematic Review and Meta-Analysis.

This systematic review and random-effects meta-analysis assessed neoadjuvant chemotherapy followed by surgery versus upfront gastrectomy in adults with signet ring cell-containing gastric cancer.

J Gastrointest CancerOct 20, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

Uniportal versus Multiportal Video-Assisted Thoracoscopic Surgery for Minimally Invasive Esophagectomy in Esophageal Cancer: A GRADE-Assessed Systematic Review and Meta-Analysis.

This GRADE-assessed systematic review and meta-analysis compared uniportal (uVATS) with multiportal video-assisted thoracoscopic surgery (mVATS) for minimally invasive esophagectomy in adults with esophageal cancer.

J Gastrointest CancerOct 15, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Association between cancer cachexia and treatment-related adverse outcomes in patients with gastrointestinal cancers: a systematic review and meta-analysis.

This systematic review and meta-analysis examined cohort studies of cancer cachexia and treatment-related outcomes in patients with gastrointestinal cancers.

Support Care CancerOct 23, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

The effect of telephone-based education and counselling on stoma adjustment and complication severity in individuals with a colostomy: a randomised controlled trial.

This randomised controlled trial evaluated telephone-based education and counselling for people with a colostomy, compared with routine stoma care.

Support Care CancerOct 22, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

Tranexamic acid in laparoscopic sleeve gastrectomy: bleeding control amid thrombotic concerns and hemodynamic instability: a randomized double-blinded clinical trial.

This randomized, double-blinded clinical trial assessed tranexamic acid (TXA) for perioperative bleeding prevention in 185 patients with morbid obesity undergoing elective laparoscopic sleeve gastrectomy.

Acta Cir BrasOct 19, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

Comparative perioperative and oncological outcomes of the da Vinci Xi versus Si robotic surgical systems in rectal cancer surgery: a systematic review and meta-analysis.

This systematic review and meta-analysis compared perioperative and oncological outcomes with da Vinci Xi versus Si systems in rectal cancer surgery.

J Robot SurgOct 20, 2026Read summary
Clinical ResearchNephrology

Peritoneal catheter fixation versus nonfixation in open surgery: A meta-analysis.

This meta-analysis compared fixation with nonfixation of peritoneal dialysis (PD) catheters placed by open surgery. Thirteen studies included 648 patients in the fixation group and 627 in the nonfixation group.

Medicine (Baltimore)Oct 16, 2026Read summary
Clinical ResearchPlastic Surgery

Efficacy of Stromal Vascular Fraction for Scar Prevention: A Multicenter, Double-Blinded, Randomized Controlled Trial.

This multicenter, double-blinded, placebo-controlled randomized trial evaluated intraoperative stromal vascular fraction (SVF) injections for scar prevention in 45 patients undergoing free tissue transfer at three…

Aesthet Surg JOct 15, 2026Read summary

Showing 12 of 23 publications that cleared our clinical screen in the last 14 days.

Looking for an earlier article?Everything that has appeared in Trending is in the archive.

Stay updated for free

Get the 3 most interesting publications in one specialty each week.

Weekly email. Unsubscribe anytime.

Want this personalized?

Stop searching the literature. Choose what you follow and xxcode will build your personalized medical digest.

  • Your specialties
  • Your filters and thresholds
  • Clinical Research + Case Reports, tuned separately
  • Automatic weekly delivery
  • Audio and text
Create my personalized digestSee plans

Prefer listening? Personalized audio digests are available with Pro.