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Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

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FeaturedClinical ResearchNephrology

Haemodiafiltration, haemofiltration and haemodialysis for adults with kidney failure.

Cochrane Database Syst RevOct 13, 2026

This Cochrane systematic review and meta-analysis assessed randomised trials comparing convective dialysis (haemofiltration, haemodiafiltration or acetate-free biofiltration) with diffusive haemodialysis or expanded…

Why it matters

The mortality findings suggest that dialysis modality may be relevant to long-term outcomes in adults with kidney failure. However, the review found no clear advantage for several patient-important outcomes, and…

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Also worth knowing

Clinical ResearchNephrology

Early exercise therapy for acute nephrotic syndrome: a randomised clinical trial.

This single-centre randomised controlled trial assessed early exercise therapy in hospitalised adults receiving glucocorticoids for acute nephrotic syndrome.

J NephrolOct 22, 2026Read summary
Clinical ResearchNephrology

Crescents in native kidney biopsies from patients with IgA nephropathy and the risk of recurrence after kidney transplantation: a retrospective cohort study, systematic literature review and meta-analysis of observational studies.

This retrospective cohort study, systematic review and meta-analysis examined whether glomerular crescents in native kidney biopsies predict IgA nephropathy (IgAN) recurrence after kidney transplantation.

J NephrolOct 22, 2026Read summary
Clinical ResearchNephrology

Local ancestry-aware genome-wide meta-analysis uncovers novel genetic loci for sickle cell disease nephropathy.

This local ancestry-aware genome-wide association meta-analysis examined estimated glomerular filtration rate in participants from two well-characterized adult sickle cell disease cohorts, seeking genetic loci…

Blood AdvOct 16, 2026Read summary
Clinical ResearchNephrology

Peritoneal catheter fixation versus nonfixation in open surgery: A meta-analysis.

This meta-analysis compared fixation with nonfixation of peritoneal dialysis (PD) catheters placed by open surgery. Thirteen studies included 648 patients in the fixation group and 627 in the nonfixation group.

Medicine (Baltimore)Oct 16, 2026Read summary
Clinical ResearchCardiology

Psychological Stress and the Diurnal Patterns of Sodium Excretion and Blood Pressure: Results From the SABRE Study.

The SABRE study examined whether urinary sodium responses to mental stress were associated with day–night sodium excretion patterns and systolic blood pressure (BP) dipping in apparently healthy adults.

J Am Heart AssocOct 16, 2026Read summary
Clinical ResearchNephrology

Recruitment, Engagement, Experiences, and Self-Reported Changes in a Digital Patient Activation Intervention to Improve Hemodialysis Session Stability: Mixed Methods Study.

This mixed methods study evaluated recruitment, engagement, completion, and participant experiences in Dialysafe, a digital education and peer-mentoring intervention at 10 hemodialysis centers.

J Med Internet ResOct 16, 2026Read summary
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