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217 articles
October 202620
Effects of E-Coach-Based Chronic Disease Management on Self-Management, Quality of Life, and Mental Health in Maintenance Hemodialysis Patients.
This randomized controlled trial evaluated a WeChat-based E-Coach programme in 96 patients receiving maintenance hemodialysis, comparing usual care plus E-Coach with usual care alone.
Crescents in native kidney biopsies from patients with IgA nephropathy and the risk of recurrence after kidney transplantation: a retrospective cohort study, systematic literature review and meta-analysis of observational studies.
This retrospective cohort study, systematic review and meta-analysis examined whether glomerular crescents in native kidney biopsies predict IgA nephropathy (IgAN) recurrence after kidney transplantation.
Early exercise therapy for acute nephrotic syndrome: a randomised clinical trial.
This single-centre randomised controlled trial assessed early exercise therapy in hospitalised adults receiving glucocorticoids for acute nephrotic syndrome.
Local ancestry-aware genome-wide meta-analysis uncovers novel genetic loci for sickle cell disease nephropathy.
This local ancestry-aware genome-wide association meta-analysis examined estimated glomerular filtration rate in participants from two well-characterized adult sickle cell disease cohorts, seeking genetic loci…
Peritoneal catheter fixation versus nonfixation in open surgery: A meta-analysis.
This meta-analysis compared fixation with nonfixation of peritoneal dialysis (PD) catheters placed by open surgery. Thirteen studies included 648 patients in the fixation group and 627 in the nonfixation group.
Recruitment, Engagement, Experiences, and Self-Reported Changes in a Digital Patient Activation Intervention to Improve Hemodialysis Session Stability: Mixed Methods Study.
This mixed methods study evaluated recruitment, engagement, completion, and participant experiences in Dialysafe, a digital education and peer-mentoring intervention at 10 hemodialysis centers.
Psychological Stress and the Diurnal Patterns of Sodium Excretion and Blood Pressure: Results From the SABRE Study.
The SABRE study examined whether urinary sodium responses to mental stress were associated with day–night sodium excretion patterns and systolic blood pressure (BP) dipping in apparently healthy adults.
Haemodiafiltration, haemofiltration and haemodialysis for adults with kidney failure.
This Cochrane systematic review and meta-analysis assessed randomised trials comparing convective dialysis (haemofiltration, haemodiafiltration or acetate-free biofiltration) with diffusive haemodialysis or expanded…
Effectiveness of a self-management intervention on clinical outcomes among patients with type 2 diabetes at high risk for Diabetic Kidney Disease: A Randomised Controlled Trial.
This prospective, two-arm randomised controlled trial at a tertiary hospital in China evaluated a structured self-management programme in 134 adults with type 2 diabetes classified as at high risk of diabetic kidney…
Sustained potassium control and recurrent hyperkalemia during individualized potassium-guided sodium zirconium cyclosilicate titration in maintenance hemodialysis: a post hoc analysis of a randomized trial.
This exploratory post hoc analysis of a single-centre, open-label randomised trial assessed sustained potassium control with individualized potassium-guided sodium zirconium cyclosilicate (SZC) in 116 maintenance…
Impact of HIF-prolyl hydroxylase inhibitors on VEGF expression and vascular adverse events in chronic kidney disease: a meta-analysis of 34 randomized controlled trials.
This meta-analysis of 34 randomized controlled trials assessed VEGF levels and VEGF-related adverse outcomes with hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) in people with chronic kidney disease.
Effects of gliflozins on bone health of patients with chronic kidney disease: a systematic review.
This systematic review assessed skeletal safety and bone-related metabolic outcomes with sodium-glucose co-transporter-2 inhibitors (SGLT2i) in people with chronic kidney disease, drawing on randomised trials and…
Disparities in GLP-1RA and SGLT2i Uptake: a Systematic Review and an Equity-First Framework for Cardiovascular-Kidney-Metabolic Care.
This systematic review synthesised U.S. evidence on disparities in prescribing and initiation of GLP-1 receptor agonists and SGLT2 inhibitors, and proposed an equity-first framework for cardiovascular-kidney-metabolic…
The effects of exercise on pulmonary function and respiratory muscle strength in patients with chronic kidney disease: a systematic review and meta-analysis.
This systematic review and meta-analysis examined experimental studies of exercise and respiratory outcomes in people with chronic kidney disease across disease stages. Thirteen studies contributed to the meta-analyses.
Artificial intelligence-powered renal pathology for glomerular disease classification: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the performance of artificial intelligence (AI) models in classifying glomerular diseases using pathology images.
Efficacy and safety of roxadustat for the treatment of renal anemia in patients undergoing peritoneal dialysis: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the efficacy and safety of roxadustat for treating renal anemia in patients undergoing peritoneal dialysis.
Bone Anabolic Treatment in Patients With Chronic Kidney Disease: A Systematic Review.
This systematic review evaluated the efficacy and safety of anabolic parathyroid hormone (PTH) treatments in patients with chronic kidney disease (CKD) Stages 4-5D.
Facilitators of Peer Support Among Patients With Chronic Kidney Disease: A Systematic Review and Qualitative Meta-Synthesis.
This systematic review and qualitative meta-synthesis examined facilitators of peer support among patients with chronic kidney disease (CKD).
Renoprotective effects and safety of sodium-glucose cotransporter 2 inhibitors in diabetic chronic kidney disease: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effects of sodium-glucose cotransporter 2 (SGLT2) inhibitors on patients with diabetic chronic kidney disease (CKD).
Mediation Analysis of Urine Osmolality and Response to Tolvaptan in Autosomal Dominant Polycystic Kidney Disease: A Post Hoc Assessment.
This post hoc analysis of the TEMPO 3:4 randomized controlled trial evaluated urine osmolality (Uosm) as a biomarker for long-term response to tolvaptan in patients with autosomal dominant polycystic kidney disease…
September 20264
Rituximab as Rescue or Add-On Therapy for Relapsing or Refractory Lupus Nephritis: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the efficacy of rituximab (RTX) as rescue or add-on therapy for relapsing or refractory lupus nephritis in 445 patients.
Anakinra versus intramuscular methylprednisolone acetate for gout flares in people with chronic kidney disease (ASGARD): a UK randomised multicentre, double-blind, double-dummy controlled feasibility study with economic, qualitative and safety assessment.
The ASGARD study was a feasibility randomized controlled trial comparing anakinra to intramuscular methylprednisolone acetate for treating gout flares in patients with chronic kidney disease.
Blood Pressure Dipping Status in Chronic Kidney Disease and Association With Adverse Outcomes: A Systematic Review and Meta-Analysis.
This systematic review and random-effects meta-analysis examined nondipping blood pressure prevalence, its association with CKD, and outcomes among people with CKD.
Effectiveness and Safety of Virtual Reality Interventions for Symptom Management in Adults Undergoing Hemodialysis: Systematic Review and Meta-Analysis of Randomized Controlled Trials.
This systematic review and meta-analysis evaluated the effectiveness and safety of virtual reality (VR) interventions for symptom management in adults undergoing hemodialysis.
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