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Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

AllClinical ResearchCase Reports
FeaturedClinical ResearchEmergency Medicine

A multifaceted intervention to increase bystander CPR rates after out-of-hospital cardiac arrest in France: a stepped-wedge, cluster-randomised, controlled trial.

Lancet Public HealthOct 21, 2026

This stepped-wedge, cluster-randomised controlled trial assessed a coordinated intervention to increase bystander CPR before EMS arrival among adults with non-traumatic out-of-hospital cardiac arrest in France.

Why it matters

Bystander CPR is an important early response to OHCA, and this trial suggests that combining dispatcher support, volunteer activation, and agency feedback can increase its use.

Read summary

Also worth knowing

Clinical ResearchObstetrics & Gynecology

Outcomes of Mindful Mood Balance for Moms, online mindfulness-based cognitive therapy for perinatal depressive relapse prevention in the USA: a two-arm, single-blind, pragmatic randomised clinical trial.

This single-blind, pragmatic randomised clinical trial tested a web-based mindfulness-based cognitive therapy programme plus usual care against usual care alone in euthymic pregnant women with recurrent depression and…

Lancet Public HealthOct 21, 2026Read summary
Clinical ResearchCardiology

Effectiveness of Discrete Strategies and Implementation Bundles for Improving Clinician Prescription of Clinical Practice Guideline-Recommended Medications for Atherosclerotic Occlusive Disease: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed randomized trials of strategies to improve prescription of guideline-strongly-recommended medications for adults with atherosclerotic occlusive disease.

J Am Heart AssocOct 16, 2026Read summary
Clinical ResearchCardiology

Global Prevalence of Adherence to Antihypertensives and Associated Moderating Factors Among Adults With Hypertension: A Meta-Analysis.

This systematic review and meta-analysis estimated global adherence to antihypertensive medication among adults with hypertension.

J Am Heart AssocOct 16, 2026Read summary
Clinical ResearchCardiology

The effects of sodium reduction and the DASH diet on ambulatory blood pressure: overall and race-stratified results from the DASH-Sodium trial.

This randomized feeding trial examined ambulatory blood pressure (ABP) responses to sodium reduction and the DASH diet in 335 participants, 58% of whom self-identified as Black.

Am J HypertensOct 15, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Combined Chatbot and Counselor Support for Smoking Cessation in China: A Pilot, Mobile-Based, Randomized Controlled Trial.

This two-arm, community-based randomized pilot trial in China assessed chatbot-supported smoking cessation and whether adding personalized counselor support might improve outcomes.

Nicotine Tob ResOct 22, 2026Read summary
Clinical ResearchPsychiatryOpen access

Randomized controlled trial of a group-based smoking cessation intervention for adults with serious mental illness.

This randomized controlled trial evaluated PARQuit in 99 adults with serious mental illness in the United States. Participants received 12 weeks of cessation counseling and pharmacotherapy and were assigned to…

Nicotine Tob ResOct 22, 2026Read summary
Clinical ResearchInfectious Diseases

Safety and immunogenicity of the 24-valent pneumococcal conjugate vaccine in healthy Chinese adults: two single-center, randomized, double-blind Phase 1 and Phase 2 trials.

Two single-center, randomized, double-blind Phase 1 and Phase 2 trials assessed the safety and immunogenicity of a 24-valent pneumococcal conjugate vaccine (PCV24) in healthy Chinese adults aged 18 years or older.

Expert Rev VaccinesOct 22, 2026Read summary
Clinical ResearchPreventive Medicine / Public HealthOpen access

Administration-order effects in head-to-head comparisons of the EQ-5D-3L and EQ-5D-5L descriptive systems: evidence from a randomised general-population panel in Great Britain.

This randomised study in a general-population panel in Great Britain examined whether administration order affects comparisons of the EQ-5D-3L and EQ-5D-5L.

Qual Life ResOct 22, 2026Read summary
Clinical ResearchCardiologyOpen access

Wireless Home Blood Pressure Monitoring With Health Coaching for Hypertension Management at a Federally Qualified Health Center: Pilot Randomized Controlled Feasibility and Acceptability Study.

This 6-month, two-arm randomized pilot trial assessed feasibility and acceptability of wireless home blood pressure monitoring (HBPM) with health coaching among adults with uncontrolled or newly diagnosed hypertension…

JMIR Form ResOct 22, 2026Read summary
Clinical ResearchEndocrinology

From Alert to Action: Electronic Practice Advisory Improves DSMES Referrals Over 18 Months.

This cluster-randomized controlled trial in primary care practices in central North Carolina tested whether an electronic health record best practice advisory (BPA) increased referrals to diabetes self-management…

Diabetes CareOct 21, 2026Read summary
Clinical ResearchPulmonology

Interventions to increase participation in lung cancer screening programmes: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed interventions to improve informed choice and participation in low-dose CT lung cancer screening.

Eur Respir RevOct 21, 2026Read summary

Showing 12 of 45 publications that cleared our clinical screen in the last 14 days.

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