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319 articles
October 202624
Local Delivery of Interferon-β1a for Respiratory Viral Infections: A Systematic Review.
This PRISMA-guided systematic review assessed locally delivered intranasal or inhaled interferon-β1a for respiratory viral infections, covering clinical trials and experimental evidence.
Dyspnea Reduction With L-Menthol Inhalation Improves High-Intensity Endurance Running Performance in Healthy Trained Adults.
This randomized, counterbalanced crossover trial tested whether L-menthol inhalation reduces breathlessness and improves high-intensity running performance in 18 trained endurance runners with normal spirometry.
Clinical Outcomes and Complications of Extracorporeal Membrane Oxygenation (ECMO) in Adult Patients With COVID-19 in Central and Eastern Europe: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis pooled observational studies of adults with COVID-19 treated with ECMO in Central and Eastern Europe. Twelve studies covered 802 patients from six countries.
A self-controlled case series to evaluate the effects of clinical trial eligibility criteria on biologic-associated reductions in severe asthma exacerbations: an analysis of the CHRONICLE study.
This study examined whether eligibility criteria used in biologic trials identify adults with severe asthma who are more likely to benefit.
The prognostic value of physical functioning on survival in patients with nonsmall cell lung cancer: a systematic review and meta-analysis.
This systematic review and meta-analysis examined whether objectively measured physical functioning predicts survival in adults with nonsmall cell lung cancer (NSCLC), across surgical and nonsurgical treatment groups.
Interventions to increase participation in lung cancer screening programmes: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed interventions to improve informed choice and participation in low-dose CT lung cancer screening.
Effects of resistance training on subjective sleep quality, excessive daytime sleepiness, and quality of life in patients with obstructive sleep apnea: a secondary analysis from a randomized controlled trial.
This secondary analysis of a randomized controlled trial examined eight weeks of resistance training in 25 adults with moderate to severe obstructive sleep apnea.
Effectiveness of physical, psychological, and alternative interventions for post-COVID-19 condition: a systematic review.
This systematic review of randomized controlled trials assessed supervised, face-to-face non-pharmacological interventions in adults with WHO-defined post-COVID-19 condition.
Safety and effectiveness of the Vertex Pulmonary Embolectomy System in acute intermediate-risk pulmonary embolism: the SPIRARE II pivotal trial.
SPIRARE II was a prospective, single-arm, multicentre pivotal trial evaluating the Vertex Pulmonary Embolectomy System for aspiration thrombectomy in patients with acute intermediate-risk pulmonary embolism.
Effectiveness of local ablative therapy combined with first-line tyrosine kinase inhibitors in epidermal growth factor receptor-mutated oligometastatic non-small cell lung cancer: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed local ablative therapy (LAT) plus first-line tyrosine kinase inhibitors (TKIs) versus TKI alone in patients with EGFR-mutated oligometastatic non-small cell lung cancer.
The Impact of Ambient Ozone Exposure on Respiratory Health in the U.S. Populations: A Systematic Review.
This systematic review synthesized U.S. epidemiologic and experimental studies published from 1980 to 2026 on acute and chronic ambient ozone exposure and respiratory health.
The effects of multiregional fascial mobilization on heart rate and physiological parameters in patients with obstructive sleep apnea: A randomized controlled trial.
This randomized controlled trial assessed the acute physiological effects of a 16-minute multiregional fascial mobilization protocol in 95 men with polysomnography-confirmed moderate-to-severe obstructive sleep apnea.
Efficacy and Safety of Necitumumab and Pembrolizumab Combination Therapy in Advanced Non-Small Cell Lung Cancer with ≥50% PD-L1 Expression: A Nonrandomized Phase II Trial.
This nonrandomized, multicenter, open-label, single-arm phase II trial evaluated first-line pembrolizumab plus necitumumab in 50 patients with previously untreated advanced NSCLC and PD-L1 tumor proportion score ≥50%.
Machine Learning, Radiomics, and Clinical Models Predicting Checkpoint Inhibitor Pneumonitis in Lung Cancer: A Systematic Review and Meta-analysis.
This systematic review and meta-analysis assessed machine-learning, radiomics, deep-learning, and clinical models for predicting checkpoint inhibitor pneumonitis in people with lung cancer.
Improvement in peripheral airway function after a 12-week exercise intervention in COPD.
This prospective, multicenter, single-arm non-randomized intervention study assessed lung function, exercise capacity and symptoms before and after a 12-week supervised exercise program in 62 people with COPD.
Effectiveness of a fully digital mandibular advancement appliance compared with CPAP in the treatment of obstructive sleep apnea.
This crossover clinical study compared a fully digital mandibular advancement appliance (MAA) with CPAP in 20 adults with obstructive sleep apnea (OSA), confirmed by polysomnography and non-adherent to CPAP.
Effect of web-based education on NIV-related side effects and insomnia severity in COPD patients using home NIV: a randomized controlled trial.
This randomized controlled trial evaluated web-based education about NIV-related side effects and insomnia management in 75 patients with COPD using home noninvasive ventilation.
Lung ultrasound-guided protocolized fluid management versus conventional central venous pressure-based management in monitoring extravascular lung water during the perioperative period of percutaneous nephrolithotomy: a randomized controlled trial.
This randomized controlled trial compared lung ultrasound (LUS)-guided protocolized fluid management with conventional central venous pressure (CVP)-based management in 181 patients undergoing elective percutaneous…
Measurement properties of pulmonary function measurement and patient-reported outcome measures in patients with multiple rib fracture without flail segment; validation study alongside the multicenter FixCon trial.
This multicenter validation study, conducted alongside a randomized controlled trial, assessed pulmonary function, pain, and health-related quality-of-life measures in 180 adults with multiple rib fractures without a…
Home-based, remotely supervised, high-intensity interval training and cardiorespiratory fitness in children and adolescents with post-infectious bronchiolitis obliterans: a randomised controlled trial.
This assessor-blinded, multicentre randomised controlled trial evaluated 16 weeks of home-based, real-time remotely supervised high-intensity interval training (HIIT) in children and adolescents aged 6–20 years with…
Effects of complementary therapies on physiological and psychological outcomes in chronic obstructive pulmonary disease patients: A systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis pooled 36 randomized controlled trials involving 3148 people with COPD to assess complementary therapies, including exercise-based and psychological approaches.
Comparative effects of inspiratory and expiratory muscle training on diaphragm adaptations and respiratory function in adolescent athletes: a randomized-controlled study.
This randomized controlled study compared inspiratory muscle training (IMT) with expiratory muscle training (EMST) in 26 adolescent female volleyball players.
Manual compared to automated closed-loop oxygen control strategies in hospitalised adults: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed randomised controlled trials comparing closed-loop oxygen control (CLOC) with manual adjustment in hospitalised adults receiving noninvasive oxygen.
The effects of exercise on pulmonary function and respiratory muscle strength in patients with chronic kidney disease: a systematic review and meta-analysis.
This systematic review and meta-analysis examined experimental studies of exercise and respiratory outcomes in people with chronic kidney disease across disease stages. Thirteen studies contributed to the meta-analyses.
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