Multiple Congenital Granular Cell Epulis Involving Different Parts of the Oral Cavity: A Case Report.

Ear Nose Throat JMar 18, 2024 (epub)
Case ReportPathology (Anatomic & Clinical)PediatricsOtolaryngology (ENT)

Yuelin Qin, Ningning Hu, Cuimei Zhang et al.

✦ AI-curated · Sources linked

Case in brief

A female neonate presented with four asymptomatic masses involving the maxillary and mandibular gingiva and tongue. Their size caused feeding and respiratory difficulties, prompting removal under general anesthesia. Histology showed tightly arranged polygonal cells with abundant granular eosinophilic cytoplasm. The cells were negative for S-100, NSE, CD68, and SOX10, and positive for AAT and vimentin. Clinical, histomorphometric, and immunohistochemical findings established multiple congenital granular cell epulis.

What made this case unusual

The lesions involved several distinct oral sites—the maxillary and mandibular gingiva and tongue—rather than a single location, and their size caused both feeding and respiratory difficulties.

Diagnostic / clinical pearl

In neonates with intraoral masses, include congenital granular cell epulis in the differential; histology and immunohistochemistry can support the diagnosis.

Source

PubMed · PMID 38499986

Published in Ear Nose Throat J. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

ShareTelegramLinkedIn

AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

More in Pathology (Anatomic & Clinical)

Clinical ResearchPreventive Medicine / Public Health

2025 National Guidelines on the Mediterranean Diet: Executive Summary of a Joint Report by Italian Scientific Societies and the National Institute of Health Task Force on Clinical Practice Guidelines.

This systematic review and practice guideline, developed by a multidisciplinary panel using NUTRIGRADE, assessed Mediterranean diet evidence across nine health domains and one economic domain.

Nutr RevNov 12, 2026Read summary
Clinical ResearchOrthopedic Surgery

Prevention of Venous Thromboembolism after Total Hip or Knee Replacement.

This multicenter randomized comparative-effectiveness noninferiority trial compared 30 days of aspirin, warfarin, or rivaroxaban for VTE prophylaxis after elective total hip or knee arthroplasty.

N Engl J MedNov 12, 2026Read summary
Clinical ResearchAnesthesiology

Effect of discontinuing antihypertensives on perioperative hypotension in older patients before non-cardiac surgery: multicentre, randomised, double blind, controlled trial.

This multicentre, randomised, double blind, placebo controlled trial assessed whether withholding ACE inhibitors or ARBs on the morning of surgery reduces perioperative hypotension in older adults undergoing non-cardiac…

BMJNov 11, 2026Read summary

Want this personalized?

Stop searching the literature. Choose what you follow and xxcode will build your personalized medical digest.

  • Your specialties
  • Your filters and thresholds
  • Clinical Research + Case Reports, tuned separately
  • Automatic weekly delivery
  • Audio and text
Create my personalized digestSee plans

Prefer listening? Personalized audio digests are available with Pro.

Stay updated for free

Get the 3 most interesting publications in one specialty each week.

Weekly email. Unsubscribe anytime.