Effect of Home-Based Palliative Care on Quality of Life in Patients With Cancer: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
Ernita Rante Rupang, Ninuk Dian Kurniawati, Huey-Ming Tzeng et al.
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In 30 seconds
This systematic review and meta-analysis assessed whether home-based palliative care improves quality of life in patients with cancer. It included eight randomized trials identified through searches of six databases up to June 9, 2024, and pooled results using a random-effects model. Home-based palliative care was associated with better quality of life than the comparison conditions, with a pooled standard mean difference of 0.45 (95% confidence interval, 0.04-0.86; P = .03). The authors concluded that quality of life improved, while noting the need for larger studies and more rigorous methods.
Key findings
- Across 8 randomized trials, home-based palliative care improved quality of life (pooled standard mean difference, 0.45 [95% confidence interval, 0.04-0.86]; P = .03).
Why it matters
Quality of life is a central goal of palliative care, and these pooled trial findings suggest that care delivered at home may support that goal for people with cancer. The result provides evidence relevant to considering home-based models alongside other care settings, while the limited evidence base means the size and reliability of benefit warrant further study.
What to keep in mind
The analysis included only 8 studies; the authors call for larger samples and more rigorous methodologies.