De Novo brain arteriovenous malformations in alcohol-related cirrhosis.
Amin Yakubu, Neil V Patel, Emanuele Orru et al.
✦ AI-curated · Sources linked
Case in brief
A 38-year-old woman with alcohol-related cirrhosis developed a de novo pial arteriovenous malformation in the left sylvian fissure. The lesion caused recurrent hemorrhages and ultimately required neurosurgical intervention. The report discusses possible links between cirrhosis, chronic inflammation, pro-angiogenic conditions, and AVM formation, while noting the management challenges posed by concurrent neurovascular and systemic disease.
What made this case unusual
The reported AVM was de novo and occurred in a patient with alcohol-related cirrhosis, prompting discussion of a possible relationship between cirrhosis-associated inflammatory and pro-angiogenic conditions and AVM formation.
Diagnostic / clinical pearl
In a patient with cirrhosis and recurrent intracranial hemorrhage, consider an underlying pial AVM; this case also raises, but does not establish, a possible association between cirrhosis and de novo AVM formation.