The Fate of False Lumen in Type B and Residual Type A Aortic Dissection Using the Candy-Plug Technique: A Systematic Review and Meta-Analysis.
Georgios I Karaolanis, Konstantinos Kotopoulos, Rosalinda D'Amico et al.
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In 30 seconds
This systematic review and meta-analysis assessed false-lumen occlusion using the Candy-plug technique in patients with type B or residual type A aortic dissection. Six eligible studies included 128 patients. Pooled technical success was 96% (95% CI, 88-98), while pooled clinical success was 76% (95% CI, 58-88). False-lumen thrombosis occurred in 71% (95% CI, 55-83), and aortic remodeling in 50% (95% CI, 33-66). The authors describe the technique as promising but note that clinical success is lower and long-term durability data are limited.
Key findings
- Across six studies and 128 patients, pooled technical success was 96% (95% CI, 88-98).
- Pooled clinical success was 76% (95% CI, 58-88).
- False-lumen thrombosis was 71% (95% CI, 55-83), and aortic remodeling was 50% (95% CI, 33-66).
- The authors report that long-term durability data are limited and recommend lifelong, strict follow-up to monitor for device-related complications.
Why it matters
The findings suggest that Candy-plug false-lumen occlusion can achieve high technical success in selected patients with type B or residual type A dissection, but technical success does not ensure clinical success or aortic remodeling. The pooled outcomes and reported reinterventions underscore the importance of assessing both procedural and longer-term results when considering this approach.
What to keep in mind
The meta-analysis included only six studies and 128 patients; the authors also note limited data on long-term device durability.