Single antiplatelet therapy and tirofiban bridged with surface modified flow diverters for ruptured blood blister-like aneurysms: single center experience and systematic review.

In 30 seconds

This study evaluated the safety and efficacy of surface modified flow diverters (FDS) combined with single antiplatelet therapy (SAPT) and tirofiban in 17 patients with ruptured blood blister-like aneurysms (BBAs). The results showed a 94.1% complete angiographic occlusion rate and 76.5% favorable clinical outcomes, with no rebleeding or ischemic events reported.

Key findings

• 94.1% of patients achieved complete angiographic occlusion.
• 76.5% attained favorable clinical outcomes (modified Rankin Scale score ≤2).
• No aneurysm rebleeding or device-related ischemic events occurred.
• No hemorrhagic complications were observed during external ventricular drainage or shunting.

Why it matters

The findings suggest that using surface modified FDS with SAPT and tirofiban may provide a safer alternative for treating ruptured BBAs, which are typically associated with high re-rupture risks and complications from dual antiplatelet therapy.