VITREOUS METASTASIS OF LARYNGEAL CARCINOMA PRESENTING AS A WHITE MASS: A CASE REPORT.
Takako Ohnishi, Mariko Horinaka, Akira Ohno et al.
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Case in brief
A 56-year-old man receiving immunochemotherapy for laryngeal carcinoma presented with two weeks of left-eye photopsia. Examination showed mild anterior chamber and vitreous cells, slight macular edema, and a white inferior vitreous mass; angiography later showed retinal vasculitis. Tractional retinal detachment and retinal hemorrhage subsequently developed, prompting vitrectomy. Histopathology of the vitreous specimen showed atypical squamous cells, establishing vitreous metastasis from the laryngeal carcinoma.
What made this case unusual
The metastasis appeared as a white, inferiorly settled vitreous mass, with few other initial ocular findings.
Diagnostic / clinical pearl
In a patient with carcinoma, a vitreous opacity—particularly a discrete white mass—may represent metastatic disease; vitreous biopsy can establish the diagnosis.