Return to Baseline Activity Following Vaginal Pelvic Organ Prolapse Repair.
Erin E Mowers, Pamela Moalli, Lauren E Giugale
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In 30 seconds
This secondary analysis of a randomized controlled trial examined recovery of functional activity after vaginal native-tissue apical prolapse repair in 65 women undergoing surgery with general anesthesia and an enhanced recovery protocol. Activity was assessed at 1, 2, 6, and 12 weeks. Return to baseline activity was reported by 52.3% at 1 week, 69.2% at 2 weeks, 84.1% at 6 weeks, and 93.6% at 12 weeks. Chronic obstructive pulmonary disease and greater intraoperative and phase 2 recovery-unit morphine equivalents were negatively associated with recovery by 6 weeks.
Key findings
- Baseline activity had resumed in 52.3% of participants by 1 week and 84.1% by 6 weeks.
- By 12 weeks, 93.6% of participants had returned to baseline activity.
- Chronic obstructive pulmonary disease was negatively associated with 6-week recovery (OR: 0.02 (95% CI, 0.001-0.43), P <0.05).
- Higher intraoperative and phase 2 recovery-unit morphine equivalents were negatively associated with 6-week recovery.
Why it matters
Recovery timelines can inform postoperative counseling after vaginal apical prolapse repair. The findings suggest that many patients resume baseline activity early, while a meaningful proportion have not done so by 6 weeks. Associations with chronic obstructive pulmonary disease and morphine use may help identify factors relevant to recovery, although they do not establish that these factors cause delayed return to activity.
What to keep in mind
This was a secondary analysis involving 65 participants undergoing vaginal apical procedures; findings may not generalize to other prolapse operations or patient populations.