FULMINANT CLOSTRIDIUM SEPTICUM ENDOGENOUS ENDOPHTHALMITIS PRESENTING WITH INTRAOCULAR GAS IN A PATIENT WITH METASTATIC ENDOMETRIAL CANCER.
Young Je Choi, Min Jeong Kwon, Hyun Goo Kang et al.
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Case in brief
A 52-year-old woman with metastatic endometrial cancer experienced sudden vision loss in her left eye following dizziness and fever. Examination revealed corneal edema and anterior chamber inflammation, while B-scan ultrasonography showed a subretinal hypoechoic lesion. Orbital CT indicated intraocular gas pockets, leading to early vitrectomy. However, progressive ocular necrosis resulted in enucleation, with Clostridium septicum identified in cultures.
What made this case unusual
The presence of intraocular gas pockets in the context of Clostridium septicum endophthalmitis is particularly noteworthy, indicating a gas-forming infection associated with malignancy.
Diagnostic / clinical pearl
Clinicians should consider gas gangrene endophthalmitis in patients with intraocular gas formation, especially those with underlying malignancies, as it necessitates urgent intervention.
Why it matters
Recognizing the association between Clostridium septicum and malignancies can aid in early diagnosis and management of this rare but severe condition.