A novel homozygous variant of AURKC causes macrozoospermia in a Chinese family.

Syst Biol Reprod MedJan 13, 2026 (epub)
Case ReportMedical Genetics

Jian Zhang, Yijia Zhao, Liwen Deng et al.

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Condensed from the publisher's abstract. An xxcode editorial summary of this publication has not been generated yet.

From the abstract

Macrozoospermia is a rare cause of male infertility characterized by a high proportion of sperm with large, irregular heads. In this study, we identified a novel homozygous Aurora kinase C ( AURKC ) missense variant (c.253G > A (p.Glu85Lys)) in a Chinese infertile man using whole-exome sequencing.

Source

PubMed · PMID 41528256

Published in Syst Biol Reprod Med. The text above is extracted from the publisher's own abstract and has not been edited by xxcode. For clinical decisions, review the original publication.

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