Clinical management of late-stage Listeria monocytogenes infection with complete placenta previa: a case report of conception in a natural cycle following stillbirth.
Tingting Wu, Lifang Ren, Limei Bian et al.
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Case in brief
A 33-year-old woman with a pregnancy conceived by in vitro fertilization presented in the third trimester with Listeria monocytogenes infection, complete placenta previa, a succenturiate placenta, and breech presentation. Despite prompt medical intervention, intrauterine fetal demise occurred. After prophylactic uterine artery embolization, she delivered vaginally. Her menstrual cycles returned to normal postpartum, and she conceived during a monitored natural cycle. The subsequent pregnancy was uncomplicated, ending in a term delivery of a healthy boy.
What made this case unusual
The case combined late-pregnancy listeriosis with complete placenta previa and other obstetric complications; after fetal demise and uterine artery embolization, the patient later conceived naturally and had a healthy term birth.
Diagnostic / clinical pearl
Listeria infection in pregnancy can have severe fetal consequences. The report also raises amniotic-fluid next-generation sequencing as a possible approach to early diagnosis, without establishing its effectiveness.
Why it matters
The reported fertility-preserving outcome after uterine artery embolization may be relevant when managing delivery in a patient with placenta previa, though this single case cannot establish general outcomes.