A case of sclerosing microcystic adenocarcinoma of the tongue: Case report and literature review.
Nusret Solak, Bahar Atasoy, Nasir Ahmad Nasir et al.
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Case in brief
A 53-year-old woman presented with an 18-month history of a painless submucosal mass on the anterior tongue. MRI showed a 14 × 15 × 10 mm ill-defined lesion, isointense to muscle on T2-weighted images and vividly enhancing after contrast. Histopathology after excision confirmed sclerosing microcystic adenocarcinoma, with perineural and muscular invasion. Because the surgical margin was close, the lesion was re-excised. She remained disease-free at 12 months postoperatively.
What made this case unusual
The tumor combined locally aggressive histological features, including perineural and muscular invasion, with an indolent clinical course.
Diagnostic / clinical pearl
Small samples may not reliably establish the diagnosis; the report recommends excisional biopsy when feasible.