Endoscopic Submucosal Dissection as a Diagnostic and Minimally Invasive Therapeutic Excision Modality for Primary Anorectal Malignant Melanoma.
Yusaku Yokotani, Hiroaki Kitae, Kyoka Ozawa et al.
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Case in brief
An 82-year-old man with primary anorectal malignant melanoma underwent endoscopic submucosal dissection (ESD), which served as a total biopsy and minimally invasive excision. The report describes subsequent adjuvant treatment with immune checkpoint inhibitors. The abstract does not provide the presenting symptoms, lesion appearance, histological details, or clinical outcome.
What made this case unusual
ESD was used both to obtain a total biopsy and to excise the anorectal melanoma, addressing the diagnostic challenge of preoperative histological confirmation while providing a less invasive resection.
Diagnostic / clinical pearl
Primary anorectal melanoma may be difficult to diagnose before surgery; in this case, ESD provided tissue diagnosis through total biopsy and excision.