Intermittently Scanned Continuous Glucose Monitoring Enhances Weight Loss and Adherence in Women with Obesity: A Randomized Controlled Trial.
Marina Gradiser, Ines Bilic-Curcic, Ines Okun et al.
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In 30 seconds
This 12-week randomized controlled trial assessed whether intermittently scanned continuous glucose monitoring (isCGM) added to a structured lifestyle programme improved outcomes in 35 women with overweight or obesity. Both groups received supervised exercise and dietary counselling; the intervention group used isCGM at an additional mid-intervention time point. Weight fell by -5.5 ± 2.3 kg in the intervention group versus -0.2 ± 1.8 kg in controls (P < 0.001), with greater improvements in BMI, body composition and dietary adherence. Time in range also improved modestly in the intervention group.
Key findings
- Weight change was -5.5 ± 2.3 kg with additional isCGM use versus -0.2 ± 1.8 kg in controls (P < 0.001).
- BMI decreased by -1.9 ± 0.6 versus -0.1 ± 0.4 kg/m 2, respectively (P < 0.001).
- Waist-to-height ratio, body fat and visceral fat improved more, while muscle mass and dietary adherence increased in the intervention group (P < 0.05).
- Clinically meaningful weight loss occurred in 35% of the intervention group versus 0% of controls; time in range improved modestly (P = 0.03).
Why it matters
The findings suggest that glucose feedback may support engagement with dietary recommendations and improve weight and body-composition outcomes when added to supervised lifestyle care. This is relevant because adherence can be a challenge in weight-management programmes. The results are preliminary, however, and do not establish whether benefits persist beyond the 12-week intervention.
What to keep in mind
The trial included only 35 women and lasted 12 weeks; the authors state that larger, longer-term studies are needed.