Injectable platelet-rich fibrin as a valid therapeutic option for inactive linear morphea (en coup de saber): report of cases.
Xuechen Ai, Jun He, Pengfei Song et al.
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Case in brief
Two patients with inactive linear morphea in an en coup de saber pattern had band-like, atrophic lesions affecting the frontoparietal area, with facial contour defects and pigmentation. Both received injectable platelet-rich fibrin (i-PRF), an autologous platelet concentrate. The report describes satisfactory aesthetic outcomes in both patients within five injection sessions. Adverse effects were limited to mild pain and transient erythema after injection.
What made this case unusual
The report describes aesthetic improvement with i-PRF in inactive en coup de saber morphea, where pharmacological treatments may not meet patients’ aesthetic expectations.
Diagnostic / clinical pearl
In inactive en coup de saber morphea with residual contour and pigmentation changes, i-PRF was associated with satisfactory aesthetic outcomes in these two cases.