Comparison of a TrachoSpray Device and Manual Lidocaine Spray on Hemodynamic Stability and Postoperative Sore Throat in Patients Undergoing Double-Lumen Tube Intubation: A Randomized Controlled Trial.
Murat Tümer, Fatih Doğu Geyik, Mesut Buz et al.
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In 30 seconds
This randomized controlled trial compared TrachoSpray-delivered lidocaine, manually sprayed lidocaine, and saline in 60 patients undergoing elective thoracic surgery with double-lumen tube intubation. Both lidocaine groups had significant reductions in systolic, diastolic, and mean arterial pressure at key time points compared with saline. After extubation, mean arterial pressure was significantly higher with TrachoSpray than with manual lidocaine spray (p = 0.04). Postoperative sore-throat scores did not differ significantly among the groups.
Key findings
- Both lidocaine groups had significant reductions in systolic, diastolic, and mean arterial pressure at key time points compared with saline.
- Post-extubation mean arterial pressure was significantly higher with TrachoSpray than with manual lidocaine spray (p = 0.04).
- Postoperative sore-throat scores showed no statistically significant differences between groups.
Why it matters
Hemodynamic responses to double-lumen tube intubation are clinically relevant, and this trial suggests that topical lidocaine delivered by either method may improve measured stability compared with saline. However, the absence of a detectable difference in sore-throat scores means the hemodynamic findings should not be interpreted as evidence that either technique prevents this postoperative symptom.
What to keep in mind
The trial included 60 patients, and the abstract reports no significant sore-throat benefit; further research is needed to confirm the hemodynamic findings and assess longer-term outcomes.