Patient and public involvement in randomized trials of lifestyle intervention among pregnant women with obesity: An umbrella review.
Elisabeth Garcia Vilaplana, Andrea Vigaray Galera, Carmen Amezcua-Prieto et al.
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In 30 seconds
This umbrella review assessed patient and public involvement (PPI) in systematic reviews and randomized trials of lifestyle interventions for pregnant women with obesity, and examined its relationship with trial compliance and follow-up. It included 11 systematic reviews, 10 with meta-analyses, covering 94 randomized controlled trials. No review reported PPI, and only 6/94 (10%) trials did. Trials reporting PPI had a higher median intervention compliance rate than those not reporting it (74% versus 68%, P = 0.637), but a lower follow-up rate (78% versus 89%, P = 0.138); neither difference was statistically significant.
Key findings
- No systematic review reported implementing PPI; 6/94 (10%) randomized trials reported PPI.
- Median intervention compliance was 74% in trials reporting PPI versus 68% in those not reporting it (P = 0.637).
- Median follow-up was 78% in trials reporting PPI versus 89% in those not reporting it (P = 0.138).
- Of the 11 systematic reviews, 3/11 (27%) were rated low quality and 8/11 (73%) critically low quality.
Why it matters
PPI may help make research more patient-centred, but this review found it was rarely reported in evidence syntheses and trials of lifestyle interventions during pregnancy in women with obesity. The observed compliance and follow-up differences were not statistically significant, so the findings do not establish that PPI improves trial participation. Clearer integration and reporting would help assess its contribution in future research.
What to keep in mind
Only 6 randomized trials reported PPI, limiting interpretation of comparisons in compliance and follow-up. The included systematic reviews were rated low or critically low quality.