Meta-Analysis of the Efficacy of Ultrasound-Guided Mammotome Minimally Invasive Surgery and Traditional Open Surgery in the Therapy of Benign Breast Tumors.
Xiaojie Liu, Wanjing Hu, Chao Yang
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In 30 seconds
This systematic review and meta-analysis compared ultrasound-guided Mammotome minimally invasive surgery with traditional open surgery for benign breast tumors. It included 8 studies involving 1,909 patients, with studies published from 2018 to 2023. Compared with open surgery, Mammotome surgery was associated with shorter operation time (MD = -12.79, 95%CI (-14.04, -11.55), P < 0.00001), as well as less intraoperative blood loss, shorter healing time, and a lower complication rate. The abstract does not specify units for the reported mean differences.
Key findings
- Operation time was shorter with Mammotome surgery (MD = -12.79, 95%CI (-14.04, -11.55), P < 0.00001).
- Intraoperative blood loss was lower (MD = -11.55, 95%CI (-14.74, -8.36), P < 0.00001).
- Healing time was shorter (MD = -2.73, 95%CI (-4.03, -1.43), P < 0.00001).
- The reported complication-rate estimate differed between procedures (MD = 0.17, 95%CI (0.12, 0.26), P < 0.00001); the abstract does not clarify the measure's direction.
Why it matters
The pooled findings suggest that, in the included studies, ultrasound-guided Mammotome surgery may offer perioperative and recovery advantages over open surgery for benign breast tumors. These outcomes are relevant when weighing procedural approaches, but interpretation depends on the underlying studies and on details not provided in the abstract, including the units and direction of some estimates.
What to keep in mind
The meta-analysis included only 8 studies. The abstract does not report study-level quality results or clarify the units and direction of the complication-rate estimate.