Systematic Review and Meta-Analysis on Rescue Stenting for Large Vessel Occlusion Due to Underlying Intracranial Atherosclerotic Stenosis.
Francesco Marino, Guglielmo Pero, Santo R Borzì et al.
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In 30 seconds
This systematic review and meta-analysis evaluated the efficacy and safety of rescue stent placement in patients with large vessel occlusion (LVO) due to intracranial atherosclerotic stenosis (ICAS). Analyzing data from eight studies involving 1901 patients, the study found that rescue stenting significantly improved 90-day functional independence (OR, 1.61) and successful reperfusion (OR, 2.47) without increasing mortality or symptomatic intracranial hemorrhage.
Key findings
- Rescue stent placement improved 90-day functional independence (mRS 0-2) with an odds ratio of 1.61.
- Successful reperfusion rates were higher with stenting (OR, 2.47).
- No significant difference in mortality was observed (OR, 0.74).
- Symptomatic intracranial hemorrhage rates did not significantly increase (OR, 1.25).
Why it matters
Understanding the benefits and risks of rescue stenting in ICAS-LVO is crucial for clinicians managing acute ischemic strokes, as it may influence treatment decisions and patient outcomes.
What to keep in mind
The evidence is limited by the small number of studies and their observational nature, which may introduce confounding factors.