Optical quality in decentration of intraocular lenses: updated systematic review.
J Cataract Refract SurgSep 24, 2026
Clinical ResearchOphthalmology
Celia Villanueva, Nuria Garzón, César Albarrán-Diego
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In 30 seconds
This systematic review evaluated the impact of intraocular lens (IOL) decentration on optical quality across various IOL designs, including monofocal, EDOF, multifocal, and toric lenses. The review included 74 studies and found that multifocal and EDOF IOLs exhibited significant reductions in image quality and contrast sensitivity with decentration, particularly at higher levels.
Key findings
- Aspheric monofocal IOLs with negative spherical aberration showed greater optical degradation with decentration compared to spherical models.
- Multifocal and EDOF IOLs were more sensitive to decentration, leading to notable reductions in image quality.
- Toric IOLs experienced significant optical quality loss when decentration was combined with rotational misalignment.
Why it matters
Understanding the effects of IOL decentration on optical quality is crucial for clinicians to make informed decisions regarding lens selection, ultimately optimizing postoperative visual outcomes for patients.