Extranodal Natural Killer/T-Cell Lymphoma Mimicking Chronic Mucormycosis.
Jun Yun, Matthew E Lin, Josef Madrigal et al.
✦ AI-curated · Sources linked
Case in brief
A 34-year-old woman presented with progressive, destructive midline facial lesions that raised concern for chronic rhinofacial mucormycosis. Tissue biopsy and pathologic evaluation instead established extranodal NK/T-cell lymphoma. Despite prompt initiation of asparaginase-based chemotherapy, her disease progressed rapidly.
What made this case unusual
The lymphoma presented with destructive facial lesions resembling chronic rhinofacial mucormycosis, creating a diagnostic challenge between malignancy and invasive fungal infection.
Diagnostic / clinical pearl
When destructive midline facial lesions suggest chronic mucormycosis, tissue biopsy and pathologic evaluation can identify an alternative diagnosis such as extranodal NK/T-cell lymphoma.
Why it matters
The case illustrates the aggressive course that may occur despite prompt asparaginase-based chemotherapy.