Cervical Vertebral Metastasis Mimicking Thyroid Uptake on Planar 123 I-MIBG Images.

Clin Nucl MedApr 2, 2026 (epub)
Case ReportNuclear MedicineOncology (Medical)

Safiya I Lahlaf, Hongming Zhuang

✦ AI-curated · Sources linked

Case in brief

A 10-year-old girl with neuroblastoma underwent 123 I-MIBG scintigraphy. Planar images showed intense neck activity that appeared more prominent anteriorly and resembled thyroid uptake. SPECT/CT localized the tracer to the C7 vertebral body, identifying osseous metastatic disease rather than physiological thyroid accumulation.

What made this case unusual

A cervical vertebral metastasis projected on planar imaging as apparent thyroid uptake, creating a potential localization pitfall.

Diagnostic / clinical pearl

When neck activity on planar 123 I-MIBG images is not clearly localized, SPECT/CT can distinguish thyroid uptake from activity arising in a cervical vertebral lesion.

Source

PubMed · PMID 41949892

Published in Clin Nucl Med. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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