Giant Pseudoangiomatous Stromal Hyperplasia Presenting as Bilateral Macromastia in an 11-Year-Old Female Patient: Emphasis on Pediatric Presentation and Literature Review.
Sydney Rashid, Mai Thy Tran, Shubha Dave
✦ AI-curated · Sources linked
Case in brief
An 11-year-old premenarchal girl presented with rapidly progressive bilateral breast enlargement, diagnosed as giant pseudoangiomatous stromal hyperplasia (PASH). The tumors measured 39.1 cm and 29.2 cm, necessitating bilateral subtotal mastectomy with free nipple grafting due to symptomatic macromastia. This case highlights the unique presentation of PASH in pediatric patients, differing significantly from adult cases.
What made this case unusual
This case is notable for the size and weight of the tumors, with a total resection weight of 15.4 kg, which is exceptionally rare in pediatric PASH presentations.
Diagnostic / clinical pearl
Clinicians should recognize that pediatric PASH can present as massive bilateral breast enlargement, distinct from typical adult presentations, necessitating tailored management strategies.
Why it matters
Understanding the unique characteristics of pediatric PASH is crucial for timely diagnosis and intervention, as it may require more aggressive treatment compared to adult cases.