Atypical presentation of severe ovarian hyperstimulation syndrome complicated by isolated pleural effusions: a case series and literature review.
Yousef Alebrahim, Karolina Palinska-Rudzka, Lewis Nancarrow et al.
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Case in brief
Three patients developed severe ovarian hyperstimulation syndrome (OHSS) characterized by large pleural effusions following medically assisted reproduction. Notably, these effusions were predominantly right-sided and occurred with minimal or absent ascites. All patients required ultrasound-guided intercostal drainage and supportive management, leading to rapid improvement. Two patients continued their pregnancies, while one did not achieve pregnancy.
What made this case unusual
The predominant manifestation of severe OHSS as isolated pleural effusions, occurring with minimal or absent ascites, is a rare presentation that warrants attention.
Diagnostic / clinical pearl
Clinicians should consider pleural effusion as a potential manifestation of severe OHSS, even in the absence of significant ascites.
Why it matters
Recognizing this atypical presentation can lead to timely diagnosis and management, improving outcomes for patients undergoing medically assisted reproduction.