Acute kidney injury, secondary to valacyclovir use during pregnancy for the prevention of fetal cytomegalovirus infection.

Int J Gynaecol ObstetApr 18, 2026 (epub)
Case ReportNephrologyObstetrics & GynecologyOpen access

Jason Brafman, Yechiel Schlesinger, Moshe Barg et al.

✦ AI-curated · Sources linked

Case in brief

A healthy young pregnant woman in her first trimester was treated with high-dose valacyclovir for primary cytomegalovirus (CMV) infection to prevent fetal transmission. She developed acute kidney injury (AKI as a result of the treatment. The condition was identified and managed appropriately, highlighting the need for monitoring renal function in similar cases.

Diagnostic / clinical pearl

Clinicians should be aware that high-dose valacyclovir for preventing fetal CMV transmission can lead to acute kidney injury in approximately 1% of cases.

Source

PubMed · PMID 41999145Free full text on PubMed Central

Published in Int J Gynaecol Obstet. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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