Successful pregnancy via assisted reproductive technology following combined high-intensity focused ultrasound, ethanol injection, and GnRH agonist therapy for refractory uterine fibroids: a case report.
Qi Wan, Qingling Wang, Xue Jiao Wang et al.
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Case in brief
A woman with multiple recurrent refractory uterine fibroids and infertility underwent two open myomectomies and four sessions of high-intensity focused ultrasonography without adequate response. She received a combination of ultrasound-guided ethanol injection and gonadotropin-releasing hormone agonist therapy. This multimodal approach led to a successful pregnancy via in vitro fertilization and the delivery of a healthy newborn.
Diagnostic / clinical pearl
A multimodal treatment strategy combining high-intensity focused ultrasound with ethanol injection and GnRH agonist therapy may improve reproductive outcomes in patients with refractory uterine fibroids.