Adnexal necrobiotic xanthogranuloma presenting as a "kissing" eyelid lesion.

OrbitApr 21, 2026 (epub)

M A Suadi, S E Detiger, D Scheers et al.

✦ AI-curated · Sources linked

Case in brief

A 50-year-old man presented with a rare form of necrobiotic xanthogranuloma, characterized by a 'kissing' lesion on the upper and lower eyelids. Previous debulking surgeries had failed, and a biopsy confirmed the diagnosis. Despite multiple corticosteroid injections, the lesions remained stable for 2.5 years post-treatment, highlighting the chronic nature of this condition.

What made this case unusual

The case is notable for the atypical presentation of necrobiotic xanthogranuloma as a 'kissing' eyelid lesion, which is uncommon in the literature.

Diagnostic / clinical pearl

Histopathologic confirmation of necrobiotic xanthogranuloma is crucial to prevent unnecessary surgical interventions and to guide appropriate systemic evaluations.

Why it matters

This case underscores the importance of recognizing atypical presentations of necrobiotic xanthogranuloma, which can mimic other lesions and may require careful management.

Source

Published in Orbit. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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