Have Iota Simple Rules the Same Diagnostic Performance When Used by Nonexpert Examiners as Compared to Expert Examiners? Systematic Review and Meta-Analisis.
J Clin UltrasoundApr 21, 2026 (epub)
Dominique Hierard, Carmen Padilla-Prieto, Claudia Arego et al.
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In 30 seconds
This systematic review and meta-analysis evaluated the diagnostic accuracy of the IOTA Simple Rules for classifying adnexal masses by expert and nonexpert ultrasound operators. The study included 30 studies and found that pooled sensitivity and specificity were 0.90 and 0.93 for experts, and 0.88 and 0.92 for nonexperts, with no significant differences in accuracy between the two groups.
Key findings
- Pooled sensitivity for expert operators was 0.90, while for nonexpert operators it was 0.88.
- Pooled specificity for expert operators was 0.93, compared to 0.92 for nonexpert operators.
- Diagnostic odds ratios were 118 for experts and 86 for nonexperts.
- Positive posttest probability was 84% for experts and 81% for nonexperts.
Why it matters
The findings suggest that the IOTA Simple Rules can be effectively utilized by both expert and nonexpert operators, enhancing the accessibility of reliable diagnostic tools for adnexal mass assessment in various clinical settings.