Effectiveness of intrauterine anesthesia on pain management during IUD insertion: A meta-analysis of randomized controlled trials.

ContraceptionApr 20, 2026 (epub)
Clinical ResearchObstetrics & Gynecology

Rebecca Fonseca De Azevedo, Ingryd de Almeida Silva, Ana Carolina Mendes Dominguez et al.

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In 30 seconds

This meta-analysis evaluated the effectiveness of intrauterine anesthesia (IUA) versus saline infusion for pain management during IUD insertion in nulliparous and parous women. The analysis included six randomized controlled trials with 651 participants. Results indicated that pain during IUD insertion was significantly lower with IUA (SMD -0.47; 95% CI -0.90 to -0.03; p = 0.04).

Key findings

  • Pain during IUD insertion was significantly lower with IUA compared to saline (SMD -0.47; 95% CI -0.90 to -0.03; p = 0.04).
  • Subgroup analysis showed significant pain reduction with lidocaine (p = 0.0002) but not with other anesthetics (p = 0.27).
  • Pain after insertion did not differ significantly between IUA and saline groups (p = 0.05).
  • All studies included had a low risk of bias.

Why it matters

Effective pain management during IUD insertion is crucial for patient comfort and satisfaction. This study suggests that intrauterine anesthesia, particularly lidocaine, may enhance the experience for women undergoing this procedure, potentially increasing the acceptability of long-acting reversible contraception.

Source

Published in Contraception. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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