Electrochemotherapy in pediatrics: a systematic review.
M A Formstone, J J Neville, A N Smith et al.
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In 30 seconds
This systematic review evaluated electrochemotherapy (ECT) in pediatric patients, analyzing 15 studies involving at least 127 children. The review found complete response rates for tumors between 97-100% and volume reductions for vascular anomalies ranging from 52% to 100%. The study highlights the potential of ECT but notes the need for further research due to methodological limitations.
Key findings
- Complete response rates for tumors treated with ECT were reported between 97-100%.
- Pooled volume reductions in vascular anomalies ranged from 52% to 100%.
- Most complications from ECT were minor, but serious events were also reported.
- The methodological quality of included studies was low, with small sample sizes.
Why it matters
Understanding the efficacy and safety of ECT in pediatric patients is crucial for clinicians considering treatment options for tumors and vascular anomalies. This review provides insights into potential outcomes and complications associated with ECT.
What to keep in mind
The review identified low methodological quality, small sample sizes, and inconsistent reporting across studies as significant limitations.