Effects of Olfactory Training on Olfactory Bulb Volume Among Patients With Non-Sinonasal-Related Olfactory Dysfunction: A Systematic Review and Meta-Analysis.
Xiangxian Liu, Xincen Jiang, Yankun Li et al.
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In 30 seconds
This systematic review and meta-analysis evaluated the impact of olfactory training (OT) on olfactory bulb volume (OBV) in patients with non-sinonasal-related olfactory dysfunction. Analyzing data from seven studies with 310 participants, the results indicated a significant increase in overall unilateral OBV by 2.14 mm³ (P < .001) following OT, with specific increases of 1.91 mm³ in patients with olfactory dysfunction and 4.22 mm³ in healthy individuals.
Key findings
- OT significantly increased overall unilateral OBV by 2.14 mm³ (P < .001).
- Patients with non-sinonasal-related OD showed an increase of 1.91 mm³ in OBV (P < .001).
- Healthy individuals experienced a 4.22 mm³ increase in OBV (P = .001).
- No significant OBV changes were observed in non-OT patients (P = .46).
Why it matters
Understanding the effects of olfactory training on olfactory bulb volume can inform treatment strategies for patients with olfactory dysfunction, potentially enhancing recovery and quality of life through neuroplasticity.